Although there are 4 amphetamines in Adderall the two that are most prominent are Levoamphetamine (the levorotory) "left-handed" enantiomer and Dextroamphetamine salts (the dextrorotory or "right-handed" enantiomer) These specifically target the two hemispheres of the brain. Simply Dex is more stimulative of the imaginative side (creative, recreative), and Levo more so to the logical side (computing, caculating). This creates a more balanced brain stimulation equation. Without this balance, chaos will ensue in the responses of the brain. I believe Dex. itself would have a higher potentional for abuse because it is stimulating the side of the brain that is more responsible for enjoyment of stimuli, whatever they may be to each sense more particulary, physical tactile sensation, visual acuity, and auditory enhancement. The more logical side of the brain (less stimulated without Levo.) is there to manage the complexity and boundries of conclusive reactions in the brain from these different enhanced stimuli from the right side. Too much Levo would amplify the left side to the point that caution becomes paranoia and drive becomes anxiety. Instead too much dex will let's say muffle the "left rotor" and you get less reasoning. By this I mean less responsible thought. The same thought that says I have had enough.. I have got to go my doctor appointment lit trying to refill this prescription today or the frequent, how many days has it been since I have slept? If you use amphetamines make it adderall. The scientists and pharmecologists mixed the salts for a specific reason and I have come to realize after the use of CNS stimulants for extended periods (Adderall, Adderall XR, Vyvanse, Dexedrine) that this reason is 100% applicable and extremely important in the long run of use be it therapuetic or recreational.
Another note. After long periods of use the logical side always wins the balancing equation. By this I mean eventually the nervous system and the nuerons in the brain that control it will downgrade themselves in a biochemical and organic way so that the more primal reactions to the senses that can be damaging or fatal are culled to an extent that varies. High doses used in recreation then become amplified logically and have less of the sensory pleasure to allow the procedure of administering higher dosages to achieved a rememered (addictive) response. This means that the brain can no longer behave anything but logically, forcing an acceptive response to protect the most important left rotory drive (without logic we cannot survive as humans) reduced to only survival instinct in the madulla oblongota (as any beast). The logical mind will create thoughts of proactivity, structure and societal ideation as a means to protect ego and identity. Meaning it will create thoughts of doubt, ego dissapation and increased drive to carry out constructive activity more so than normal. Once the compromise of these components of identity is detected (and ignored) the left side will over-compensate its funtion (ecspecially but not neccessarily on Levoamphetamine) and create over-exaggerated senses of severity in daily activities. Normal choices are thought to hold more signifigant consequences in reality. Trust issues are created amongst previously reliable engagements with events or people. Private issues are thought to become common knowledge. Possible pshycosis and schizophrenic episodes (effective and non-effective) are the cause for this. In study and personal reference these conditions are not noticed as disorders by some one who is previously un-diagnosed or unaffected by them. In fact once the transition is made a seperate believeable (to the affected mind) reality is maintained however illogical it is. Psychosis, schizophrenia and major sustained (life long) depression from stimulant changes in the brain are clinically and medically indistiguishable from traditional forms. Symptoms except for sustained major depression (horrible!) are most commonly reversable with abstinence and/or the medications one or in combination (Depakote, Haldol, Zyprexa..yuck) A very difficult thing to endure for a time, usually weeks after onset. Any one can imagine what these conditions mean from brief references in reading, movies, or TV ...however the truth that nothing can explain except experience is that these disorders debilitate daily function and quality of life more so than even any doctor can know with the vast medical knowledge available. To me seperate mixtures of amphetamine salts only increase the risks of problems with the coherency of the mind in harmony with the two distinct hemispheres of the brain. I firmly believe adderall was formulated to reduce these types of potential nuerological problems. If not then I still believe that I am correct in this observation.