Of course drugs such as these have been widely used for a very, very long time, and quite possibly to counteract these issues. But the thing with the older generations is they seem to be a lot more resilient, and I doubt many would even have the vocabulary to describe many of these issues we so widely and eagerly medicate. They just "got on with it"
I'll use my grandparents as an example: they have not had an easy life, my grandad grew up in extreme poverty, he saw a lot of action in the war, and could quite possibly qualify as having ptsd; but he's never taken an antidepressant, or therapy in his life. Neither has he ever expressed dissatisfaction with life. In fact, he's reluctant to seek medical help for any reason; he just "gets on with it". This is the reason I really admire the "old school" folk, and would like to emulate their coping mechanisms.
Of course, I'm a modern man, and well schooled in medication culture. Plus, I'm a druggy, of course......