• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio | someguyontheinternet

Deliberate ingestion of isopropanol

wungchow

wungchow

Bluelighter
Joined
Dec 12, 2006
Messages
893
Location
nyc
I've always been curious about alcohols besides ethanol. 100 mL of 40% ethanol generally provides threshold effects for me. Assuming I have pure IPA, and that it is roughly 2x as potent as ethanol, would ingesting 25 mL of IPA be a worthwhile experiment?

From reading toxicology articles I gather that treatment for IPA intoxication is largely supportive (like ethanol) and as long as I don't overshoot the dose, I'll be fine.
 
wungchow said:
I've always been curious about alcohols besides ethanol. 100 mL of 40% ethanol generally provides threshold effects for me. Assuming I have pure IPA, and that it is roughly 2x as potent as ethanol, would ingesting 25 mL of IPA be a worthwhile experiment?

From reading toxicology articles I gather that treatment for IPA intoxication is largely supportive (like ethanol) and as long as I don't overshoot the dose, I'll be fine.
Click to expand...

as long as you don't mind stinking of acetone or having a hangover from hell then probably.
 
I've found the needed dose to be about 1/3rd the dose of ethanol, mind you I did not try it many times, it's so terrible. A 5% 330mL beer is about 16 grams ethanol, so 3 of those beers is 48 grams ethanol.
25mL should provide easily noticeable effects.
You will find your breath stinks of acetone for up to 12 hrs afterward :| (it's not pleasant).
 
I figured the acetone breath would be pretty vile.

Ah well, I'll finish off this beer instead. Maybe another time.
 
Don't listen to them, the taste/scent of acetone is fruity and delicious as far as solvents go. It's about in the same league as ethanol or isopropanol.
 
So is EtOEt, but it doesn't mean people won't wonder what the devil you were up to if you go around giving off enough fumes to blow the doors in ;)
 
The ether breath was a killer. My roommate used to get high off my breath when I was talking to him after an ether binge.

Glad I don't fuck with that shit anymore.
 
This acetone breath reminds me of the times I've injected sloppily cleaned amphetamine... gives such an acetone taste in the mouth. Not unpleasant, very much like ethanol actually.
 
This acetone breath reminds me of the times I've injected sloppily cleaned amphetamine... gives such an acetone taste in the mouth. Not unpleasant, very much like ethanol actually.
Click to expand...

Huh, Any noticeable alteration in psychoactivity?
 
I've deliberately ingested 2-propanol (isopropanol) a few times as an experiment, after exhaustive research revealed that it wasn't overly toxic... only slightly more so than ethanol, but was about 2x more potent than ethanol and lasted longer.

I can confirm that it's 2x more potent than ethanol, but these things are subjective.

The buzz was pretty much indistinguishable from ethanol for the first few hours, but after that it becomes much more sedating.

The hangover is a bitch though, and leaves you smelling like acetone for a few days (acetone is the primary metabolite of isopropanol). I think it's the nasty hangover that has prevented it from becoming a viable substitute for ethanol in desperate situations (or a source of inebriation for underage kids).

I doubt there has been much study on this, but based on the acute subjective effects (they're very similar to ethanol), isopropanol probably effects most of the same receptors as ethanol. I can say with high confidence that it's a GABA(A) agonist, since the effects associated with that pharmacological action are definitely present prominently.
 
Yea I did this a few times and I almost overdosed one time on the isopropnaol. It might be fun to use a booster for regular alcohol no more then 25 ml of it. I felt crappy the time i had too much ,but it didn't feel anywhere as near as bad as the time I o'd on bendrly(I was sick for a fucking week.) Really I'm just concred it could do damage to your brain quicker then ethanol ,but I have nothing to back this up with so use common sense if you try and it and don't mix it with other drugs.
 
i think your thinking of methanol. methanol turns into formaldehyde and formic acid. ISO turns into acetone. unless im mistaken. im jw, how does the taste compare to ethanol?
 
mr.dopeman said:
i think your thinking of methanol. methanol turns into formaldehyde and formic acid. ISO turns into acetone. unless im mistaken. im jw, how does the taste compare to ethanol?
Click to expand...

You are correct, well, it metabolizes to acetone and lactic acid (both of which are probably less toxic than acetaldehyde, the main metabolite of ethanol). Acetone is produced naturally in the body during times of high catabolism of fatty acids.

Taste is similar to ethanol, slightly sweet and fruity but mostly solventy, I've only tasted a tiny bit out of curiousity and haven't consumed any large amount yet.
 
yea i havent tried any im sorta freaked out by the prospect of drinking rubbing alcohol. i was freaked out enough the first time i drank my homebrew. i was thinking id wake up blind or some shit.
 
Nuke, did I read that right? I SWEAR I read a 'yet' in there.

Drinking acetone? you gotta be shitting me, maybe my eyes are just strained, but I'm sure I read a 'yet' in that sentence...

I wouldn't fancy it myself, schizo ex gf years back drank some in a suicide attempt (at least I think thats what it was), didn't kill her, but put her in hospital.

That said I don't know how much she drank, its not the sort of thing you ask your GF when she comes out of hospital for that sort of thing :/

And surely, its a bit of a waste of time for a GABA agonist buzz, unless its quite qualitatively different from EtOH.

Ether on the other hand, now that is tasty.
 
You must log in or register to reply here.
Top