There are two reasons why you should not mix alcohol with hydrocodone. They are both CNS depressants and two much of either can send a person into a coma or you can even die. Another thing is these pills contain acetaminophen which is hard on your liver. Taking with alcohol causes an additional strain on the liver.
Using cocaine with alcohol can create problems because cocaethylene is formed when the two metabolize causing stress on your heart and liver. The effects of taking cocaine and alcohol are far more dangerous than taking either drug alone. If you feel that you are in danger, you should seek medical attention.