• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe |

Cross Tolerance/Diminished Effect

yellow_sunglasses

yellow_sunglasses

Bluelighter
Joined
Mar 11, 2009
Messages
452
Location
Toronto Area, ON
I have a music festival coming up and I normally never take psychs any more often than twice a month - so I am unclear about cross tolerance. I will be taking 2c-b, LSD, MDMA, 4aco-dmt in that order, one each day. I know that all four of these have a similiar mechanism of action, and that I will experience a diminished effect.

I am curious to what extent the effects will be diminished, I know that there is no exact answer but I would just like an idea on what to expect. Any help would be greatly appreciated=D

*note to mods - I posted this in the cross tolerance thread but recieved no answer, I just wanted to see if I could get an answer on here*
 
mdma has a mechanism of action that is not similar to the rest.

2c-b, lsd, and 4-aco-dmt are all 5HT-2a agonists, and will display cross-tolerance.

every body is slightly different when it comes to tolerance and cross tolerance. have you taken these chems before, ie do you know your 'standard' no-tolerance dose?

at the top of the forum there is a tolerance sticky, look in there. generally the rule is, 24 hours after a dose, you require 200% the original dose to get the same effect. so one day after dropping 2 tabs of acid, you need to drop 4 tabs (of the same acid) in order to have the same trip.

of course there are other variables such as mental health, physical health, sleep deprivation (it's a hell of a trip in itself, and usually you don't get much sleep if you're up all night tripping)
 
hey thanks for the reply. I have taken lsd, mdma and 4aco-dmt before, so I know my regular dose. I have not taken 2c-b before so I will be taking it first to avoid any tolerance.

Okay that 200% makes sense, thankyou. :)

Do you think that taking 2c-b two days before and lsd one day before taking MDMA will significantly affect my roll? Health and sleep aside.
 
it should not affect your roll as 2c-b does not (significantly) release serotonin to the effect that mdma does.

be sure to treat your body right so your mind will be in top shape. quality food, plenty of water and sleep.
 
You must log in or register to reply here.
Top