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  • BDD Moderators: Keif’ Richards

Harm Reduction Creating an abuse deterrent nasal spray to prevent IM/IV use

chemconnoisseur

Greenlighter
Joined
Feb 20, 2026
Messages
30
Hey! I’ve found ketamine to be highly therapeutic and a fantastic anti-depressant when properly utilized. However I’ve also abused it via IM and IV quite frequently. Nasal use rarely lead to any extreme abuse, it was only when I used needles that things became problematic. I’m looking to revisit its anti-depressant effects after a 3 month break, but do not want to slip into old habits, especially considering I’ve been doing very well getting clean off of opioids and stimulants, and now spend most of my days sober, only occasionally enjoying some mild gabergics like gabapentin and pregabalin. I still have needles around as I use steroids and peptides, which is yet to be an issue.

So the question is: what could be added to a nasal spray solution so that it couldn’t be injected, but would retain its absorption into the mucus membranes? I could see xanthan gum being a plausible solution, although I can’t think of much else. My other options are to have the dosage controlled by a friend or locking up my syringes. I’d prefer to be able to administer on my own terms, although I can see how that’s a bit more likely to cause problems.

Mods if this question is a little too risky please delete this, I’m simply posting for the sake of harm reduction.
 
Hey! I’ve found ketamine to be highly therapeutic and a fantastic anti-depressant when properly utilized. However I’ve also abused it via IM and IV quite frequently. Nasal use rarely lead to any extreme abuse, it was only when I used needles that things became problematic. I’m looking to revisit its anti-depressant effects after a 3 month break, but do not want to slip into old habits, especially considering I’ve been doing very well getting clean off of opioids and stimulants, and now spend most of my days sober, only occasionally enjoying some mild gabergics like gabapentin and pregabalin. I still have needles around as I use steroids and peptides, which is yet to be an issue.

So the question is: what could be added to a nasal spray solution so that it couldn’t be injected, but would retain its absorption into the mucus membranes? I could see xanthan gum being a plausible solution, although I can’t think of much else. My other options are to have the dosage controlled by a friend or locking up my syringes. I’d prefer to be able to administer on my own terms, although I can see how that’s a bit more likely to cause problems.

Mods if this question is a little too risky please delete this, I’m simply posting for the sake of harm reduction.
Honestly its a weird question but seems to be focused on harm reduction so.... i dunno. maybe its ok. I do worry about what crazy ideas people may propose though that end up making it even more dangerous if you were to slip up.

The problem is most things you would add to a liquid nasal spray to make it non injectable would probably make it unsnortable. The xantham gum isn't a terrible idea assuming it doesnt interfere with mucal absorbtion.

Have you ever tried sublingual ketamine? It's quite effective and probably less abuseable than snorting or injecting. I assume youre not getting prescribed?
If so maybe you could take your ketamine, weigh into separate doses and put the doses into chewing gum? Chew the gum a bit and hold under tongue?
I dunno just an idea..

I know sublingual tablet things are usually what people get sent when they do at home/online ketamine therapy via companies like nue life (which I guess shut down)
 
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