Confused about amphetamine psychosis

[TrainerGold7]

Ok so everything I've read around these forums and ones like this that talks about amphetamine psychosis say how it starts occurs after taking high doses days in a row without sleep. Well on some other sites that are more like medical sites I guess just simply say "abusing amphetamines can lead to amphetamine psychosis".

So does that mean you can get amp psychosis just from abusing them like once or twice a week for months or years? Like does it eventually just catch up with you and start making you crazy or is taking doses days in a row without sleep the only way it can occur? Because I've abused adderall/vyvanse for like a year but I take a few days off before I use them again (well I've binged for a couple days but only on a few occasions). Thanks for any input

 

[Allein]

I think all possibilities are true, prolonged continuous use will almost certainly end in psychosis, stay up for a week on amphetamines and you will be very likely to suffer the symptoms of psychosis infact its almost a certainty

But some people can suffer psychosis from a single dose even of its not that big, I guess it all depends on the state of you mind when you take the drug, I've seen people lose it totally on what was a relatively small quantity of amphetamine to the point they had to be sectioned but they were very disturbed to begin with.

Its not like we are all the same so reactions are gong to vary wildly from person to person

 

[pbuilder]

stimulant psychosis in my opinion is generally always caused by a cross between binge-ing, and of course sleep deprivation from the binge-ing.

Stay up on coffee for 48 hours if you can, see how whacked out you begin to feel. And that's just from a weak stim like caffeine. Sleep deprivation makes the mind begin to go insane, which I think goes hand and hand with "stim psychosis", which is a fancy word imo for sleep deprivation. (caused by bingeing)

I don't really think you will get stim psychosis if you have a regular sleeping pattern and use stims everyday.

If this did occur, then I doubt amphetamines would be described for multiple doses, daily use, to treat ADD and ADHD patients.

As long as you sleep, generally you should keep your sanity.

 

[Pjkt2501]

^ This, aside from the discounting of the chemical actually having an effect. In addition to sleep deprivation the drug IS playing a large role in damaging tissue and changing the mental state of the user. Saying that being awake on day 4 and feeling nutty is only due to a lack of sleep - and not the large amount of methamphetamine consumed - is a bit absurd.

 

[nAON]

Amphetamine psychosis usually refers to the acute symptoms, as has been mentioned. Of course, there are still associated problems with neurotoxicity that occur with chronic abuse of amphetamines, but it's very rarely referred to as psychosis.

 

[Pjkt2501]

So to say, someone could be a complete nutter from meth but have a perfectly a-ok brain? Interesting... I figure that either the sleep deprivation OR (well, and* imo) the drug has to be doing some irreversible damage.

 

[hgwells]

Ok so everything I've read around these forums and ones like this that talks about amphetamine psychosis say how it starts occurs after taking high doses days in a row without sleep. Well on some other sites that are more like medical sites I guess just simply say "abusing amphetamines can lead to amphetamine psychosis".

So does that mean you can get amp psychosis just from abusing them like once or twice a week for months or years? Like does it eventually just catch up with you and start making you crazy or is taking doses days in a row without sleep the only way it can occur? Because I've abused adderall/vyvanse for like a year but I take a few days off before I use them again (well I've binged for a couple days but only on a few occasions). Thanks for any input

I have had a few bouts with "stimulant psychosis", um, with one big dose of a-pvp (fist time I have ever tried it, and the last) I got really fucked up- but
then I had a two day panic attack, the only thing that could calm me down was lots of booze. Now on the other hand, I have been using 4FA almost every day for the last three weeks, and I actually feel fine,-
I have found that stimulant psychosis depends greatly on what kind of comedown a drug has- less of a comedown, fewer shakes, and the ability to sleep on it, are very important.

 

[Allein]

I've seen full, blown psychosis within hours of taking a relatively modest dose of Amphetamine sulphate, I knew the person and they definitely had issues prior but they were stable before dropping the speed. Amphetamines are prone to setting off paranoia and psychosis in those with existing problems in very short order I've seen this more than once.

Staying up for days on them its almost a dead certainty you'll have symptoms but if you already have issues you should steer well clear IMO.

 

[Mugz]

i was convinced that the police where on the balcony outside my 3rd floor flat, so they must have used a cherry picker to get up there, and you cant even get in from the outside, but that didn't stop my delusions, convinced myself flatmates had unllocked my door and they were coordinating with the window police to get me with no route to escape. Not sure why I have a police fear as I have only legal drugs in the flat, nothing that the police would even care about. That, and the ridicolousness of the police being on my balcony steered me away, although I do need slleep now, haven't slept properly since thursday night now, getting silly

 

[Pjkt2501]

Get some food and get some sleep mate. It'll do ya some good!

 

[Allein]

Hey Mugz, you know you shouldn't be fekin about with stims, your track record on paranoid delusions isn't exactly squeaky clean now is it :D

Take care of yourself my man, an what the fek have you been experimenting with this time around ? not JGG I hope

 

[Doug2113]

i was convinced that the police where on the balcony outside my 3rd floor flat, so they must have used a cherry picker to get up there, and you cant even get in from the outside, but that didn't stop my delusions, convinced myself flatmates had unllocked my door and they were coordinating with the window police to get me with no route to escape. Not sure why I have a police fear as I have only legal drugs in the flat, nothing that the police would even care about. That, and the ridicolousness of the police being on my balcony steered me away, although I do need slleep now, haven't slept properly since thursday night now, getting silly

When I first started using meth, I thought EVERYONE was a cop after being up for more than 3 days...If I was driving, I would take the longest, most sporadic, out-of-the-way possible route, and anytime I would make a turn at a red light and someone behind me made the same turn, it would just amplify my paranoia...I was doing a lot of the shit and staying up for a while though...(I've lost 20 lbs. in 3 days from doing the shit-no lie).

If you make yourself eat (which I was unable to do) and drink sport drinks/healthy alternatives (water really does nothing for you when on meth, you have to drink it constantly) AND get some fucking sleep (but yes, I know getting geettered out can be fun at times) then you should have nothing to worry about...

 

[THC2LSD]

Usually it happens after staying up for days or high doses, but some susceptible individuals might get psychosis from even theraputic dose. Rare, but it happens. Neurotoxicity doesn't usually play a role, it's the high levels of dopamine/adrenaline that cause it. It usually clears up once the drug wears off, but you might still think some of it was real for days later. Sometimes it can induce a prolonged psychosis lasting weeks, rare but happens.

Use sane doses, eat and sleep to reduce the side effects of meth. Hunger and sleep depravation can really exacerbate meth's side effects, probably most of them come from sleep depravation.

 

[TrainerGold7]

Amphetamine psychosis usually refers to the acute symptoms, as has been mentioned. Of course, there are still associated problems with neurotoxicity that occur with chronic abuse of amphetamines, but it's very rarely referred to as psychosis.

Are some of the things from neurotoxicity similar to amp psychosis?

Thanks for the replies. So it seems amphetamine psychosis is generally from too high of a dose ,sleep deprivation or both. That means it woulnd't be permanant right?
I've only been through amp psychosis once after taking one large dose in the very early days of my useageand it lasted like a day. On the few 3 day binges I've done i surprisingly havn't run into a psychosis. I don't binge anymore but I still want to make sure abusing adderall (30-80mgs) like 1 or 2 days a week doesn't just one day make me permanantly crazy lol

 

[NeighborhoodThreat]

A good amount of amphetamine psychosis has less to do with the amphetamines and more to do with the whole not sleeping and not eating aspect of amphetamine use.

Using amphetamines if you have pre-existing psychiatric issues can bring out psychosis in some people. Moderate, responsible use of amphetamines is not likely to cause amphetamine psychosis.

 

[eeklekins]

Are some of the things from neurotoxicity similar to amp psychosis?

Thanks for the replies. So it seems amphetamine psychosis is generally from too high of a dose ,sleep deprivation or both. That means it woulnd't be permanant right?
I've only been through amp psychosis once after taking one large dose in the very early days of my useageand it lasted like a day. On the few 3 day binges I've done i surprisingly havn't run into a psychosis. I don't binge anymore but I still want to make sure abusing adderall (30-80mgs) like 1 or 2 days a week doesn't just one day make me permanantly crazy lol

Psychosis is unrelated to neurotoxicity, at least in terms of dead neurons. Neurotoxicity from high-dose amphetamine use looks like Parkinson's disease. Psychosis is an acute (temporary) condition caused by totally screwed-up neurotransmitter levels,and goes away when they return to (sort of) normal.

 

[justcurious1234]

I usually experience it when I smoke meth and hardly sleep for extended periods of time. I actually just experience this over the weekend. I have been rolling for 3 weeks smoking no less then a T a day. I smoked a qrtr oz with my man this weekend and got extremely paranoid and delusional to the point I was convinced he has been booty calling me for the last yr (he has proposed 2 times now and moved me into his home lol) and was just using me so I hated him and wanted him out of my life. I told him all this via like 40 texts btw :/ He has crashed already and basically is avoiding me until I do
I have slept some each night but the most sleep I have gotten in a 24hr period is 5hrs last Sunday. Out of the 3 weeks I have only been forcing down dinner. I am drinking tons of water and no booze.
When I used to slam I used every single day just 1 to 4 shots a day for over a year and never experienced anything like I am now. I have never had a problem with the dope mind fucking me until I became a smoker and only when I use for more than a week on very little sleep.
I hope I am starting to make sense and if no I apologize, I am still a little coo coo for cocoa puffs

 

[TrainerGold7]

ok thanks for all the answers guys this clears everything up for me

 

[CockLobster]

Amphetamine psychosis is a result of overload of dopamine on D2 receptors. D2 is the receptor that is blocked by antipsychotics; positive symptoms of Schizophrenia would be alleviated by this. Taking multiple D2 agonists for prolonged periods as well as having potentially high levels of Dopamine naturally could potentially lead to amphet psychosis

 

[tweex]

Amphetamine psychosis is a result of overload of dopamine on D2 receptors. D2 is the receptor that is blocked by antipsychotics; positive symptoms of Schizophrenia would be alleviated by this. Taking multiple D2 agonists for prolonged periods as well as having potentially high levels of Dopamine naturally could potentially lead to amphet psychosis

5-HT2A is another important target in psychosis, there's some kind of interplay with D2. I'm guessing temporary dopamine downregulation from amphetamines leads to the same effects this paper talks about: http://www.ncbi.nlm.nih.gov/pubmed/21921840

Practically speaking, atypical antipsychotics do an excellent job of combating stimulant/sleep deprivation psychosis, particularly the hallucination component. I've been up around ~60h on meth+2-FMA+provigil+antipsychotics once, and functioned extremely well with basically no distortions in perception, just had to find creative ways of keeping food down. Delusions/paranoia are a bit less effected by antipsychotics, but I've found combined alpha/beta blockers take away most of the paranoia, leading me to suspect it is more rooted in norepinephrine stimulating said receptors.