Heroin Comparing Non-IV Routes

[Cane2theLeft]

Recently we've seen a lot of threads popping up asking about heroin routes of administration other than the intravenous one.

I thought it'd be good to have a thread where people can rate what they find the most efficient so when the topic comes up in the future, we can have a large reservoir of experiences and views in one place on this topic.

So what have you found regarding the intranasal (snorting), intrarectal (plugging), inhaled (smoking/vaporizing) and oral routes?

Conversely, what drawbacks and potential harm do these routes also present?

Thank you in advance to all who contribute.

 

[socio]

Snorting and plugging seem roughly equally useful to me, snorting being perhaps slightly more euphoric (but possibly only in my small sample of experiences), but plugging being more comfortable and easier in my experience. Simple: one shot and done. Rather than snorting, choking, coughing, eyes watering, repeat.... repeat.

 

[Captain.Heroin]

Snorting, by far. The 8 hour duration is very worthwhile.

 

[Cane2theLeft]

^do you find the duration the only reason that its the optimal choice? Is it more or less potent insufflated than smoked/plugged in your experience?

 

[waldo777]

My friend told me to vote for snorting which in his experience has given the best results in all categories. (has IM'd other opiates but never IVed anything, including heroin)

1) Its quick and easy to do: no real preparation needed, no obvious tools required such as lighters, tin foil, needles, bottle caps, oral syringes and lube, etc...

2) It works real well EVERY TIME, and practically no experience or research is required (aside from dosage) to do it, as opposed to the other ROA, for example;

Smoking: hard to master technique, results vary with skill level whereas w/ snorting it ALL goes up the nose and if you can breath you can snort

Plugging: requires research and experience, very variable results due to technique and amount of fecal matter up there. Plus one has to be able to set aside 20 minutes to lay on their side to plug.

Oral: don't even think swallowing heroin to get high works, (my friend was curious about the possibility of letting the heroin sit in water for a few days so that it hydrolizes (sic?) Into morphine and 06-MAM and whatever else and then orally ingesting that solution. BUT totally depends on those compounds being significantly more BA orally than heroin and I don't know the answer to that....maybe someone else does?)

The only drawback is that if your nose is a mess like my friend's, then snorting becomes less desirable

 

[Cane2theLeft]

Oral: don't even think swallowing heroin to get high works, (my friend was curious about the possibility of letting the heroin sit in water for a few days so that it hydrolizes (sic?) Into morphine and 06-MAM and whatever else and then orally ingesting that solution. BUT totally depends on those compounds being significantly more BA orally than heroin and I don't know the answer to that....maybe someone else does?)

In your other thread I explained that hydrolysis has nothing to do with oral consumption. It has to be left in a solution for quite some time for hydrolysis to occur. Metabolism and hydrolysis are entirely different processes.

When you consume heroin orally, it metabolizes into morphine (as it does from every route) before it crosses the blood brain barrier (unlike every other route) so consuming heroin orally is for our intents and purposes, essentially the same thing as consuming morphine orally.

They both have poor oral BA's but they work.

As for women, what about the vagina? I really dont think it would work because the vagina kills most germs and is acidic, but just curious if anyone knows if it might work? 8)

I can't comment on efficacy of this route, but I wouldn't want to be putting unsterile street drugs in that area personally.

 

[Dolomiti]

In your other thread I explained that hydrolysis has nothing to do with oral consumption. It has to be left in a solution for quite some time for hydrolysis to occur. Metabolism and hydrolysis are entirely different processes.

When you consume heroin orally, it metabolizes into morphine (as it does from every route) before it crosses the blood brain barrier (unlike every other route) so consuming heroin orally is for our intents and purposes, essentially the same thing as consuming morphine orally.

They both have poor oral BA's but they work.



I can't comment on efficacy of this route, but I wouldn't want to be putting unsterile street drugs in that area personally.

It metabolizes into 6 monoacetyl morphine, which is not the same thing as morphine. (if it was, why not call diacetylmorphine "morphine" instead of "heroin"?) Black tar contains a lot of 6MAM.

 

[Cane2theLeft]

^when consumed orally, heroin metabolizes into both morphine and 6-MAM. I was never claiming 6-MAM and morphine were the same thing.

When the potency difference is accounted for, the pharmacological effects of heroin do not differ appreciably from those of morphine. Heroin is metabolized to 6-acetylmorphine and morphine. After oral administration of heroin, morphine but not heroin or 6-acetylmorphine is detected in blood. In this case, heroin is a prodrug for the delivery of systemic morphine.(source)

 

[catsandstuff]

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1429907/pdf/brjclinpharm00230-0066.pdf
A very sexy study on oral morphine vs oral diamorphine

 

[windycorners]

Definitely snorting, but smoking is pretty nice also. I don't understand the whole plugging thing.

 

[Cane2theLeft]

*mod note*

ANY derisive or especially homophobic comments about the intrarectal route of administration will result in infractions. We get it, you're uncomfortable with your sexuality and we've heard all this bullshit before. If you have any inclination to comment about plugging in a way that does not contribute to harm reduction discussion about efficiency, potency and risks associated with the RoA, please kindly exit the thread.

 

[windycorners]

Before I started injecting I snorted my heroin and I love being able to really taste good dope, getting that drip go down my throat, brings back good memories.. The negative side of it was my lungs really got messed up after over a year of sniffing close to a pack a day.

 

[Sorce]

does snorting the H actually increase the duration by a lot compared to IVing?

 

[Captain.Heroin]

^do you find the duration the only reason that its the optimal choice? Is it more or less potent insufflated than smoked/plugged in your experience?

I have never plugged heroin (if I had to bother mixing it in water, I would just IV it). I also only have used powder heroin so I haven't bothered smoking it but a half dozen times at the most.

Smoking it to me only lasted one third to one half of the duration of IV heroin (by comparison it was wayyy shorter than snorted heroin).

As far as potency, I would say snorting beats smoking it. More of it hits you quicker due to smoking it, but it almosts feel like you are only getting part of the effects. Snorted heroin, once it all hits you and you are peaking, is more potent IME.

Good question Cane.

So snorting lasts longer than if you plug it? Did I understand correctly?

I tried drinking a little bit once because I couldnt shoot and it didnt feel anything. so I dont know how else orally you can take it.

As for plugging, I have no shame in doing something like that, which I think Ill give it a try next time. I just wanna get high, who cares!

As for women, what about the vagina? I really dont think it would work because the vagina kills most germs and is acidic, but just curious if anyone knows if it might work? 8)

I have never plugged it before. I have no shame either lol, I would just IV it because I am like that

does snorting the H actually increase the duration by a lot compared to IVing?

Oh yes. For me, IV heroin is a 2 to 3 hour long experience, maybe 4 hours tops - and tends to be dose dependent. For snorting, I always got a 6 to 8 hour duration, if I used enough to get a good high going.

 

[Cane2theLeft]

Thanks for the thorough contributions, CH! I was hoping we could get a lot of good experiences in here and you've certainly helped us get started on the right foot!

 

[John_Burrows]

I think the Captain needs to take one for the team and at least try plugging once. For the purposes of empirical comparison, of course.

Come on, you KNOW you're curious!

 

[Cane2theLeft]

Although I'm sure we've had several repeat viewers, this thread has been viewed 196+ times already and we only have 23 votes in the poll.... get out and vote, motherfuckers or P. Diddy will put a cap in your ass.

 

[titicaca2]

Well I've never plugged, and I get tar, so snorting is out of the question. Well its possible. But far trickier than breathing in a powder. So maybe I'm a little biased to my vote of smoking.

But it became an almost secondary addiction. The taste. The feel. The foil. It was all quite pleasant.

 

[bollox]

As for women, what about the vagina? I really dont think it would work because the vagina kills most germs and is acidic, but just curious if anyone knows if it might work?

I happened to come across this trip report on Erowid a few years ago: http://www.erowid.org/experiences/exp.php?ID=26033 Unfortunately, the "experiment" doesn't include the use of heroin. But intravaginal administration is indeed a legitimate ROA although it is most often used for treatment of localized problems such as infections. But who knows how effective or sanitary it might be.

 

[ATLL765]

Oh yes. For me, IV heroin is a 2 to 3 hour long experience, maybe 4 hours tops - and tends to be dose dependent. For snorting, I always got a 6 to 8 hour duration, if I used enough to get a good high going.

You seem to be fairly sensitive to opiates and I'm jealous because if I ever could feel a high hours after shooting, I'd be the happiest man on Earth lol.

I don't want to vote on this poll though because I don't really have enough experience with any ROA other than IV, I mean I think I snorted dope for the first week after I first tried it, after that it was IV or nothing...