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Mental Health Coming off Invega/Xeplion (paliperidone) injections v. 10

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TonyTonyChopper said:
terrible idea. Just because antipsychotics block dopamine , the D2 to be specific, it doesn't mean you can just take D2 agonist to reverse the side effects. The brain is alot more complex and it doesn't work like that. People already tried D2 dopamine agonists like cabergoline and pramipexole and it made their symptoms 10x worse.
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Really? How? Could you explain more? Clopixol is a dopamine antagonist, it binds to dopamine receptors. Apomorphine is a dopamine agonist with a stronger affinity level than clopixol,it should compete with clopixol and bind to the dopamine receptors instead of it. I also looked up some of the interaction and it says that apomorphine reduce the therapeutic efficacy of clopixol so it should work right? There's also a guy's post in this site once and it says it helps with the sexual side effects.I'm in a emergency situation, I was falsely diagnosed and forcefully Injected with something has absolutely nothing to do with me. The effects are making me suffer and I'm looking for a solution. Could you explain more about why it won't work? I need more information on this.
 
Matthew01 said:
Really? How? Could you explain more? Clopixol is a dopamine antagonist, it binds to dopamine receptors. Apomorphine is a dopamine agonist with a stronger affinity level than clopixol,it should compete with clopixol and bind to the dopamine receptors instead of it. I also looked up some of the interaction and it says that apomorphine reduce the therapeutic efficacy of clopixol so it should work right? There's also a guy's post in this site once and it says it helps with the sexual side effects.I'm in a emergency situation, I was falsely diagnosed and forcefully Injected with something has absolutely nothing to do with me. The effects are making me suffer and I'm looking for a solution. Could you explain more about why it won't work? I need more information on this.
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I looked all over reddit for ppl who took D2 dopamine agonists and logically you would think they'd fix issues like anhedonia because these D2 agonists like cabergoline and pramipexole work the exact opposite of antipsychotics by increasing dopamine at D2 where antipsychotics block them but there is rarley any1 who benefitted from these D2 dopamine agonists. Infact pramipxole is shown to worsen them. It is up to you if you wanna mess with more drugs but id say don't do something you will regret.

I personally took parnate because lots of ppl said it cured their anhedonia but that shit almost killed me, got severe psychosis after not sleeping for 8 days.
 
TonyTonyChopper said:
I looked all over reddit for ppl who took D2 dopamine agonists and logically you would think they'd fix issues like anhedonia because these D2 agonists like cabergoline and pramipexole work the exact opposite of antipsychotics by increasing dopamine at D2 where antipsychotics block them but there is rarley any1 who benefitted from these D2 dopamine agonists. Infact pramipxole is shown to worsen them. It is up to you if you wanna mess with more drugs but id say don't do something you will regret.

I personally took parnate because lots of ppl said it cured their anhedonia but that shit almost killed me, got severe psychosis after not sleeping for 8 days.
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I'm going to try it out. I feel absolutely horrible. I find it hard to enjoy music like I use to and I feel emotionless. It also severely me reduced my sexual desire. That clopixol injection messed me up for no reason and i have to fix things. I felt like my life was over when It was first given to me. I don't have anything so I don't think it will give me psychosis. Also someone told that dopamine agonist mimic and replace actual dopamine and it would lead to a shutdown in all natural dopamine production and a down regulation of dopamine transporters. Is this true? He claims to be in the medical field and he also said it would worsen my issues in the long run. I find it hard to believe because I think dopamine agonists have been used to treat the side effects of antipsychotics before.
 
InvegaAnon said:
I'm not completely back to normal, would you say that I'm subhuman?
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I’m queer and nonbinary too and I used to express that through fashion and art and humor and a flamboyance that doesn’t feel natural to me anymore. Like the gifts God gave me are gone. It makes me sad. And like if I can’t be that then I don’t feel human. Subhuman might be the wrong word. Soulless maybe. Like my inner essence is wrapped in polyurethane. And I can’t live like that. I wish I could. It’s too hard every day is a battle.
 
rawbanana said:
I’m queer and nonbinary too and I used to express that through fashion and art and humor and a flamboyance that doesn’t feel natural to me anymore. Like the gifts God gave me are gone. It makes me sad. And like if I can’t be that then I don’t feel human. Subhuman might be the wrong word. Soulless maybe. Like my inner essence is wrapped in polyurethane. And I can’t live like that. I wish I could. It’s too hard every day is a battle.
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I know it's hard, but it will get better. Even a longhauler from here got better recently. If it helps anything, I've been dressing more flamboyantly than ever since I came out.
 
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Matthew01 said:
I'm going to try it out. I feel absolutely horrible. I find it hard to enjoy music like I use to and I feel emotionless. It also severely me reduced my sexual desire. That clopixol injection messed me up for no reason and i have to fix things. I felt like my life was over when It was first given to me. I don't have anything so I don't think it will give me psychosis. Also someone told that dopamine agonist mimic and replace actual dopamine and it would lead to a shutdown in all natural dopamine production and a down regulation of dopamine transporters. Is this true? He claims to be in the medical field and he also said it would worsen my issues in the long run. I find it hard to believe because I think dopamine agonists have been used to treat the side effects of antipsychotics before.
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Is what he is saying true? He claims to be in the medical field.
 
I’m so heartbroken. I don’t think I have the strength to keep waiting for things to get better when I can’t even distract myself with simple pleasures like music or TV. Dying in this way is the ultimate tragedy too. It feels so wrong. Why does it have to be this way?
 
Apparently I can get stoned on Invega, took 50 mg worth of weed gummies and had a fun time last night night.
 
Hello people It does get better . I am one of the living proof of that . I got injection in 2018 total of 3 and it took around 2020 for me to feel somewhat normal but my interest came back and the anhedonia was lifting from me. Now I am in a much better place in life I have heen stabled for 4 years I also able to function like normal with a different feeling and view about life .everything won't be the same like before the injection but you will be able to eventually start back enjoying life again.
 
I started shaking I think I might be developing TD... not sure if I should stop taking St Johns Wort. If you haven't already I recommend researching Terry Davis for entertainment. RIP.
 
invega011024 said:
I started shaking I think I might be developing TD... not sure if I should stop taking St Johns Wort. If you haven't already I recommend researching Terry Davis for entertainment. RIP.
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I would recommend taking vitamins supplements that supports nerve system and just let the medication work out of your system you can try anything you want but until it has ran it course you pretty much have to adapt to the side affect of it . Trust me I have been there with it and it is a light at the end of the tunnel it takes about 2 - 3 years for your body to bounce out of whatever that stuff has done but I am now semi back to normal I have enjoyment and pleasure back and interest I feel 1000% better now .
 
WildSunShin3 said:
Hello people It does get better . I am one of the living proof of that . I got injection in 2018 total of 3 and it took around 2020 for me to feel somewhat normal but my interest came back and the anhedonia was lifting from me. Now I am in a much better place in life I have heen stabled for 4 years I also able to function like normal with a different feeling and view about life .everything won't be the same like before the injection but you will be able to eventually start back enjoying life again.
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Thanks for coming back to comment. It means a lot. Are you saying the injections removed your delusions and psychosis for good?
 
invegetable said:
Thanks for coming back to comment. It means a lot. Are you saying the injections removed your delusions and psychosis for good?
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I am going to give you the ugly and good truth . I didnt take anymore medication after the injects because I just wanted to be back to normal so I didnt want to chance that with adding more medication on top of what I was going through . One day it's like I snapped out of it and felt normal but the delusion and psychosis did come back . Unfortunately had after 2 years just being unstable and at my worse I had to get on another medication but it wasnt injections I feel 1000% better no anhedonia my libido has came back i feel like a different type of normal I can't really explain it but it feels good . I am not on alot of medication to manage my schizoaffective bipolar type i am only taking zyprexa 15mg and that keeps me sane but still quirky with my spirituality and belief system I am not numb and emotionless anymore it varies from people to people if this will be a permanent fix for them or not but what I am trying to say nothing is compared to what that medication did so I did what I had to do to get stable and I feel better then ever I am not going to tell you to stay off medication because it does help if you have the severity of delusional thinking and psychosis like I did but dont feel like it is a bad thing if you do have to take a different medication for right now you dont need it but when I tell you it does hit you like a bomb when you snap out of whatever the hell that shot did to you it like a veil of numbness lifted off of you it experience and can be a rough ride as well .
 
WildSunShin3 said:
I am going to give you the ugly and good truth . I didnt take anymore medication after the injects because I just wanted to be back to normal so I didnt want to chance that with adding more medication on top of what I was going through . One day it's like I snapped out of it and felt normal but the delusion and psychosis did come back . Unfortunately had after 2 years just being unstable and at my worse I had to get on another medication but it wasnt injections I feel 1000% better no anhedonia my libido has came back i feel like a different type of normal I can't really explain it but it feels good . I am not on alot of medication to manage my schizoaffective bipolar type i am only taking zyprexa 15mg and that keeps me sane but still quirky with my spirituality and belief system I am not numb and emotionless anymore it varies from people to people if this will be a permanent fix for them or not but what I am trying to say nothing is compared to what that medication did so I did what I had to do to get stable and I feel better then ever I am not going to tell you to stay off medication because it does help if you have the severity of delusional thinking and psychosis like I did but dont feel like it is a bad thing if you do have to take a different medication for right now you dont need it but when I tell you it does hit you like a bomb when you snap out of whatever the hell that shot did to you it like a veil of numbness lifted off of you it experience and can be a rough ride as well .
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Wow interesting that you had a sudden recovery, I had assumed it was gradual. I asked because if it did clear your delusions for good, that would would mean it changed the way your mind fundamentally works, which is scary to me. I actually read some of your past comments and have always had similar delusions but they never got the best of me unless I went on a sleepless drug bender which is more or less what got me this time. Anyway thanks for coming back to give us hope, we're all in severe need of it.
 
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