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Mental Health Coming off Invega Sustenna (Paliperidone) v3

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Sbar25 said:
Is this really what life is like without dopamine? It strongly binds to the receptors. Will it unbind?
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Yes, your brain will recover.

Hopefuldopeful said:
What was your psychosis story like? Delusions, paranoias, etc?
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Well, I had depressive psychosis, so a general feeling of being unwanted

Anyway, I made it clear I was taking the pills, but they just really wanted to push that injection on me
 
You will eventually recover. I haven't seen anyone who hasn't recovered with time so far.

Take solace in the fact that Invega does not completely block dopamine signalling. Of the 5 dopamine receptors in your body, paliperidone only binds to two of them: D]2 and D3 receptors. The dopamine receptors that provide stimulating/focusing/reinforcing effects (namely D1) are not blocked.
 
sekio said:
You will eventually recover. I haven't seen anyone who hasn't recovered with time so far.

Take solace in the fact that Invega does not completely block dopamine signalling. Of the 5 dopamine receptors in your body, paliperidone only binds to two of them: D]2 and D3 receptors. The dopamine receptors that provide stimulating/focusing/reinforcing effects (namely D1) are not blocked.
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Good information.
 
sekio said:
You will eventually recover. I haven't seen anyone who hasn't recovered with time so far.

Take solace in the fact that Invega does not completely block dopamine signalling. Of the 5 dopamine receptors in your body, paliperidone only binds to two of them: D]2 and D3 receptors. The dopamine receptors that provide stimulating/focusing/reinforcing effects (namely D1) are not blocked.
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I thought it was a cortico-limbic thing in D2 providing pleasure but D1 being conscious of it and giving agency, if that makes sense.
 
Why do emotions feel non existant?
We can heal into a better version of ourself from this traumatic expierence.
We will all heal 110% and be grateful for a sliver of life that most people will be unaware of
 
I remember vividly a day where I could still feel the extreme depression caused by Invega. Then about a month later the depression lifted.
 
is their a return to wholeness and a feeling of being connected to life? right now everything feels disconnected.
once the drug leaves your system is their any possibility of brain chemistry not being able to return to normal??
once the drug is not clogging receptors does dopamine flow freely once again?
anhedonia is the major problem for me right now.
it feels like everything is dull and unpleasurable and it is overwhelming hard to handle.
I want to be able to go on hikes again and feel connected to nature and get enjoyment from things.
Is that the effect of invega? Does it rob your life of day to day pleasure?
One would think once the drug is eliminated and your receptors get unclogged your brain readjusts.
Just like how when you drink a beer or smoke a cigarette you feel effects temporarily, then return to normal the next day.
the problem is this drug stays in your muscle forever and then brain takes forever to readjust.
its almost like my patience and calmness of life has been robbed or something.
does the brain readjust or does it get used to the drug and has a hard time readjusting.
 
Man, everything will be like before after the drug is out of our bodies. The fact that this drug stays for such a long time in us, we know it, and I think you said this before too and also I think you are repeating some ideas over and over and also I feel like this thread is starting to be toxic for me and I’m taking a break from checking it so often. I will update monthly maybe. Godspeed for all
 
one thing I have been thinking about is, since drugs effect everyone SIMILARLY everyone on invega is going through this nightmare of not really being able to pinpoint what the drug feels like except.... something is not right.
its hard to say WHAT EXACTLY the drug feels like. I just KNOW something isnt right but there isnt any words to describe it.
I believe by one year the poision will be gone.
Then the countdown for for receptors to heal starts.
what is the average healing time?
 
Sbar25 said:
what does eveyone do to pass time and get through their days?
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Try to read if possible.

I know music won't affect you the same way, you might crave sugar and end up binge eating. Personally, I think the D2 hypothesis is flawed but I'm not looking to get into a debate here. You might also listen to really intense music to try and feel something.
 
I used to be a clean freak I think my dopamine was really high I would do projects around the house all day and binge clean.
Now its like a different world putting clothes away feels weird and disgusting.
What is this DRUG! what D2 Hypothesis?
Is there any one chemicals that invega effects besides dopamine and serotonin?
Why are emotions blunted? Is it Dopamine related?
 
It sucks that We have to be Suffering from Invega while the virus is going on this is just a bad situation we are in guys.
This thread is a good support group though It feels good knowing other people are going through the hell of invega and knowing we can
and we will be better some day.
 
awesome31311 said:
Well, invega is a legitimate form of medication for some patients with psychosis. It has helped my brother in the past, for example.
Fluoride does not "destroy" your pineal gland, based on current scientific literature. If your pineal gland is destroyed you will have brain damage, possibly death.
Invega is a dopamine antagonist, which is the property that causes most of its side effects. The problem comes with people being forced to take it without having the side effects explained to them. Otherwise, I'm sure they would have fewer lawsuits.

The sex drive is killed mostly due to its capacity to increase prolactin.



Yes, it's very bad. What's bad is that he is not communicating well with you. Unless something serious has happened on his end preventing him from messaging you, then I'm certain you deserve someone better. If he can't be there for you during your darkest time, then that's a learning experience.

But don't overthink it. He could just be busy.
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Ugh, you’re so lucky to be improved so well. This is a nightmare that has no end to it. I’m so tired of waking up everyday. I wish I’ll never wake up. I hate it. I mean when does it get better. I mean I want my emotions more than anything. Okay no I want my life back more than anything. I hope it comes soon. Please God help me.
 
Schitzoaffective. About 5 months off Invega. When on Invega, I just laid in bed with my eyes closed for 20 hours a day. I didn't want to do activities of daily living. Now I worked my way up to working 20 hours a week...but then got laid off because of Corona virus. I'm much better now than on Invega, but my motivation and energy levels still aren't where they need to be. I don't know if it's left over Invega or negative symptoms of schitzoaffective disorder. Currently not taking antipsychotics and a little paranoia has returned. I just hope I can keep a lid on it with no psychosis because I can't live on antipsychotics. I won't be able to work, have relationships, do anything. Might as well be dead. All the advice I can give is to exercise...build yourself up to walking for at least 2 hours. I did 2,3, then 4. 4 sucked...it was like 8.8 miles. My goal is to be able to work full time. Oh, and all the weight I gained on Invega is not going anywhere. That's the second biggest kick in the balls. How the hell can I work all this off if I can't run? Walking or working it off will take 10 years. Not going to starve myself AKA diet.
 
Invega9976 said:
Schitzoaffective. About 5 months off Invega. When on Invega, I just laid in bed with my eyes closed for 20 hours a day. I didn't want to do activities of daily living. Now I worked my way up to working 20 hours a week...but then got laid off because of Corona virus. I'm much better now than on Invega, but my motivation and energy levels still aren't where they need to be. I don't know if it's left over Invega or negative symptoms of schitzoaffective disorder. Currently not taking antipsychotics and a little paranoia has returned. I just hope I can keep a lid on it with no psychosis because I can't live on antipsychotics. I won't be able to work, have relationships, do anything. Might as well be dead. All the advice I can give is to exercise...build yourself up to walking for at least 2 hours. I did 2,3, then 4. 4 sucked...it was like 8.8 miles. My goal is to be able to work full time. Oh, and all the weight I gained on Invega is not going anywhere. That's the second biggest kick in the balls. How the hell can I work all this off if I can't run? Walking or working it off will take 10 years. Not going to starve myself AKA diet.
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I know what you mean about weight. I’ve tried fasting multiple times and has lost. It’s so hard to fast on invega. I swear before invega I could eat anytime I wanted. Now I eat and I feel sick all the time. I just wish I could lose the weight at least. This is torture. I’m sick now because I ate too much today. If we don’t lose the weight from invega I don’t think we will recover. It’s so sad I’m like this. I want to cry but I’m too tired to do that. I’m 3 months off and feel defeated by invega. Invega took over my body and I can’t fight it. It’s too powerful. I just don’t want to wake up anymore. If God won’t heal me then please take my soul already. I beg you God take me. I’m tired
 
Paula10 said:
I know what you mean about weight. I’ve tried fasting multiple times and has lost. It’s so hard to fast on invega. I swear before invega I could eat anytime I wanted. Now I eat and I feel sick all the time. I just wish I could lose the weight at least. This is torture. I’m sick now because I ate too much today. If we don’t lose the weight from invega I don’t think we will recover. It’s so sad I’m like this. I want to cry but I’m too tired to do that. I’m 3 months off and feel defeated by invega. Invega took over my body and I can’t fight it. It’s too powerful. I just don’t want to wake up anymore. If God won’t heal me then please take my soul already. I beg you God take me. I’m tired
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It will get better...just wait. Worse thing is being on it...just remember that.
 
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