Mental Health Coming off Invega Sustenna (Paliperidone) v3

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I'm about 4 months off of Invega and I was wondering if someone could chime in on whether or not alcohol is safe to drink at this point?
In my opinion is not such a big problem.You can drink like 3 beers and see how you feel..At 2 months off I was able to get drunk. I hope at 6-7 months off I will be able to go to partyes again and try to do only alcohol and cigs (which is kind of difficult)
 
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antagonist irreversible receptor. Does anyone know anything about the changes to biochemistry and if it is permanent. some said once antagonist irreversible receptor it doesn't come back? Who knows anything about humans this.
 
I'm about 4 months off of Invega and I was wondering if someone could chime in on whether or not alcohol is safe to drink at this point?
Can you get drunk?
I’m 3 months off and I got really sick with drinking and there was no buzz for me.
 
Four months isn't much time...

Do you take other medications? Drugs?

I'd give it a good couple years to get back to baseline. You don't need anything messing with your chemistry as you find your center again.
Do you know if lifeline ever recovered from invega?
I’m so scared at this point. I can’t make it. I know I can’t.
 
Does anyone know anything about the changes to biochemistry and if it is permanent. some said once antagonist irreversible receptor it doesn't come back? Who knows anything about humans this.

Paliperidone is not an irreversible antagonist, it will bind and dissociate like any other. It does have a very high affinity for dopamine receptors and a long half life though, so it just seems like it lasts forever.

However, even compounds that are irreversible antagonists don't produce permanent effects. After a while your body will recycle the receptors that have been permanently activated (or deactivated), as part of the normal housekeeping and regenration your body does. This can take a long time, on the order of a few months, before all receptors are totally restored.

Do you know if lifeline ever recovered from invega?

I would imagine that he did, but that's because I'm being optimistic :) It seems to me that basically everyone who has dealt with the awful effects of Invega will recover to a functional state. It's not going to happen overnight, but it will happen gradually. I think it will actually help if you try convincing yourself you can get through this - a positive attitude sounds cheesy but it's proven to help people recover from almost any major disruption in life. It certainly does the mind better than ruminating on why you don't deserve to feel good. Those thoughts don't do anything but drag you down.

I can’t make it. I know I can’t.

Take it one day at a time. You have made it this far, and things aren't getting any worse, are they? I know you have it in you to conquer this demon and come out a better person.

Here's an experiment I try with people who experience mental "damage" from drugs: try coming up with a list of things you have done that make you feel good, and things you could do to make your life better, even simple ones. Even if you have only done basic tasks like shopping or having a shower, congratulate yourself for being able to do it. You may find that you are capable of a lot more than you give yourself credit for. And doing simple things to make you feel good not only focuses your mind on constructive, positive thinking, but also helps retrain your nucleus accumbens (the reward center of the brain) to feel good about things that benefit you. One of the effects of antipsychotics is that they will reduce signalling in this reward/pleasure area, so things that used to engage you, now feel dull and joyless, and positive thinking / exercise / gameplay / joking / music / sex / daydreaming, etc all will help restore your sensitivity to dopamine.
 
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So manny people are suffering from this invega fucking sustenna..I’m getting tired to fight with this shit..I mean I just realised that everyday I feel the same anhedonic-depressing feeling in the air..in 6 days I’ll be 3 months off this drugs and I can say that I’m better than 3 months ago like I’m getting used to it more and sometimes I’m fine like I forget somehow abot this but right now I’m thinking that I still have a long way to go ( and I got only 3 shots) and I don’t fucking know how I will make it..it’s unbelievable..other days I’m positive about all this and I encourage myself and other but right now I’m down, I don’t know how the hell I’ll make it..just existing like this is fucked up
 
Do you know if lifeline ever recovered from invega?
I’m so scared at this point. I can’t make it. I know I can’t.

As sekio said, take things daily. It's these sort of challenges that can lead to a much greater human vitality once you begin to surmount them.

Why are you saying a couple of years to get back to baseline

That's a decent safety time, barring addiction (in which case it would be never), that you might want to wait before dabbling in any other drugs. You want your brain to reset to homeostasis, and it won't do so if you feed it more non-prescribed substances. Coffee and nicotine and teas are generally thought to be safe.
 
It's so difficult having a blank mind on invega. I can think about what I want to do but that's about it. It makes living an awful struggle, I often find myself just standing or sitting on a chair doing nothing, waiting for thoughts to come into my head
 
U can recover and be back to your old self by me it take 9 10 months to be my self back and in the 12 month u good to go. Just be patience Don’t stress to much stay close with your loved ones
Yes this is true. Took me 7.5 months to feel totally normal again. Felt much better at 6.6. Everything came back. Lost all my weight. Can get high etc. super high sex drive. Just gotta go through hell then you’ll be ok.
 
You will most likely recover, but there is a chance you will not. It is that simple. Recovery will most likely take between 6-18 months, depending on the number of shots/dosages you received. I am just shy of 4 months, and I have not recovered.
It doesn't make sense how this medication works. Once it's out of your system shouldn't your brain begin the process of restoring what is gone?
 
U can recover and be back to your old self by me it take 9 10 months to be my self back and in the 12 month u good to go. Just be patience Don’t stress to much stay close with your loved ones
Did you feel any difference at month 6. I mean does it get better. I hear people do recover but I’m scared I could be the one that don’t recover. I’m so weak everyday. I wish I had at least my energy back. I wish every moth you could get back something you’ve lost. Did you have windows and waves. I’m had no improvements so far I’m 3 months off.
 
U can recover and be back to your old self by me it take 9 10 months to be my self back and in the 12 month u good to go. Just be patience Don’t stress to much stay close with your loved ones
How did you lose the weight? Did your metabolism come back and you kept dropping the pounds or did you exercise or fast. Did the everlasting hunger go away?
Anyone who has recovered please answer me. Thanks
 
Yes this is true. Took me 7.5 months to feel totally normal again. Felt much better at 6.6. Everything came back. Lost all my weight. Can get high etc. super high sex drive. Just gotta go through hell then you’ll be ok.
How did you lose the weight? Did your metabolism start back working like before and you dropped pounds quickly or did you exercise and fast? Did you have windows and waves? How did you know you were recovering from this? Please explain in details for the newcomers. Thanks
 
Yes this is true. Took me 7.5 months to feel totally normal again. Felt much better at 6.6. Everything came back. Lost all my weight. Can get high etc. super high sex drive. Just gotta go through hell then you’ll be ok.

Did you get your conversational and social skills back?
 
I had 2 shots a little over 11 months ago and still suffering from this hell. I really hope there is an end to this soon because I WILL not continue living like this. I hear people say they’ve recovered but I just don’t see how it seems impossible
I’m so scared
 
I understand you Paula..all I want to say is to be calm and patient..that’s all you can do ( this is all we can do), with time you will feel better and will recover completely. Have faith.
 
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