I almost am astonished that no one brings up how anhedonia is a major symptom in shizophrenia and how we get this shot because of a psychosis. Psychosis is a difficult puzzle to put together but I feel like with time in most cases it heals. I’m just saying idk why it’s so strictly put on the shot when in fact it’s also a symptom of major depression and schizophrenia which should be dealt with ssris regardless of side effects
Nobody had anhedonia until neuroleptics/antipsychotics(APs) were invented
!
Theory of negative symptoms is just what
pharma manufacturer's made (and teach on colleges) as
self protective mechanism.
Paliperidone mechanism of action:
is
opposite of heroin, molecular structure is the same except they use Flourine which acts antagonistc and is
very aggressive with
much more lasting effects since it sticks to receptors and won't let go which also gives
metabolic stress to receptors protein which aren't "unbreakable/unchangeable" thus causing changes which
affect their functionality in long term even after quitting, resulting in inflammation since microglia will be detecting receptor damage and sending many
repair messages to neuron cells, they also assist in replacing synapses and replacing receptors.
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I'm 2 years off and still experience severe anhedonia, around halfways recovered from it, and still recovering, noticing some progress every month, especially visible every 4 months.