Mental Health Coming off Invega (Paliperidone, Xeplion) injections v. 7.0

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You only had one injection youll be fine dude, there are people here like me whos taken 10 injections and recovering well. Be positive :)
I still had to take pills for a couple of months tho. :( did you lost your ability to cry on the first injection?
 
neuroscientists kinda know how brain works


Around 18% to 54% of people taking antipsychotics get drug induced parkinsonism (DIP) with hospital populations the highest amount. Some studies indicate 54%. Up to 30% of patients with DIP may develop a persistent or progressive parkinsonian syndrome (PPS). This literally indicate consistent and continuous damage to the dopaminergic systems.

Lets say you grab 1000 patients taking antipsychotic and median of 35% of them get DIP that's roughly 350 patients. 30% of those patients get PPS that's roughly 115. So for each 1000 people taking antipsychotics 115 get chronically ill and develop damage to the dopaminergic system. Roughly 10,5% doesn't recover. I personally think numbers for paliperidone depots are at the highest rate because paliperidone is known to cause DIP. Also hospitals where they force haldol injections would probably have highest percentage of people affected. You don't have to have a high dose or high dosage frequency to develop it.

If you assume 54% DIP rate for paliperidone shots its close to 200 cases with PPS per 1000 taking those shots. That's roughly 20% who doesn't recover at all.

At higher dosages it's accompanied by neuroleptic induced deficit syndrom (NIDS) which is another syndrom that manifest with high dosages of antipsychotics (especially depot shots)


Recovery rates and chances on recovery can probably estimated by observing how many DIP and NIDS symptoms people develop and how severe those particular symptoms are. @dirtyinvega mentioned he developed fullblown parkinsons in high intensity. Another user on youtube (with almost no recovery at year 4) also complained about severe EPS (extrapyramidal symptoms / movement disorders ) and burning pain in the brain (burning brain syndrome). If you don't develop these symptoms including NIDS in high intensity chances are high you're going to (partially or full )recover.

Just my 5 cents
 
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I still had to take pills for a couple of months tho. :( did you lost your ability to cry on the first injection?
I really cant tell you that because I didnt have anything to cry about or anything like that but I did have flat emotions and just numb feeling. Pills is nothing even if you took it for couple months you can recover from pills in just 1 week trust me. Give it some time you'll be way better in 4-6 months :)
 
I really cant tell you that because I didnt have anything to cry about or anything like that but I did have flat emotions and just numb feeling. Pills is nothing even if you took it for couple months you can recover from pills in just 1 week trust me. Give it some time you'll be way better in 4-6 months :)
My brother who took abilify 10 mg for one month took a fullblown year to recover
 
Oh cool, hows your recovery been do you feel like you're back 100%? I dont know if you mentioned your recovery before on the thread must of missed it if you did
Hey yeah I have, but I don't post in this thread daily. I honestly tend to get a lot of flack for my opinions, but I still want to help however I can. I would say I'm back to normal, whatever that is lol. I take another ap now. Things are looking up for me. Hope y'all see better days.
 
Hey yeah I have, but I don't post in this thread daily. I honestly tend to get a lot of flack for my opinions, but I still want to help however I can. I would say I'm back to normal, whatever that is lol. I take another ap now. Things are looking up for me. Hope y'all see better days.
Thats good if you think the benefits of the AP out weigh the side effects in your conculsion then you should continue taking it. For me yes I don't want to get psychotic again which is why I probably should take AP's, yes I dont wan't mania, I dont want delusions and stuff but I also dont want to live with the side effects that give me Anhedonia, akathisia emotional numbness, depression... I'm kinda left in the middle if I go right I fall into a ditch if I go left I also fall into a ditch... so I really don't know what to do but for me in a more broader opinion I don't think the benefits of AP's outweigh the risks. Because having my core receptors to live are 90% blocked makes me unable to live a productive life and not fuction day to day it really cripples my brain. I dont think its okay to fix one problem but then more problems arise which are worse than the first problem.
 
Thats good if you think the benefits of the AP out weigh the side effects in your conculsion then you should continue taking it. For me yes I don't want to get psychotic again which is why I probably should take AP's, yes I dont wan't mania, I dont want delusions and stuff but I also dont want to live with the side effects that give me Anhedonia, akathisia emotional numbness, depression... I'm kinda left in the middle if I go right I fall into a ditch if I go left I also fall into a ditch... so I really don't know what to do but for me in a more broader opinion I don't think the benefits of AP's outweigh the risks. Because having my core receptors to live are 90% blocked makes me unable to live a productive life and not fuction day to day it really cripples my brain. I dont think its okay to fix one problem but then more problems arise which are worse than the first problem.
Sounds very wise! And I respect your personal opinion.

I will say that it can take months for them to work fully. I don't think many people know this, not assuming, just saying.
 
Thats good if you think the benefits of the AP out weigh the side effects in your conculsion then you should continue taking it. For me yes I don't want to get psychotic again which is why I probably should take AP's, yes I dont wan't mania, I dont want delusions and stuff but I also dont want to live with the side effects that give me Anhedonia, akathisia emotional numbness, depression... I'm kinda left in the middle if I go right I fall into a ditch if I go left I also fall into a ditch... so I really don't know what to do but for me in a more broader opinion I don't think the benefits of AP's outweigh the risks. Because having my core receptors to live are 90% blocked makes me unable to live a productive life and not fuction day to day it really cripples my brain. I dont think its okay to fix one problem but then more problems arise which are worse than the first problem.

What antipsychotics have you tried? I dont get any actual side effects from zyprexa. Well i might ned a higher dose of a psychedelic to trip but thats about it. It even stops some of the morphine itch i get.

I wouldnt take invega or abilify again though fuck them. They shuld only be used when literally nothing else works. I would just take thorazine if i got that bad as ive had that before and its actually good when mixed with morphine.
 

Around 18% to 54% of people taking antipsychotics get drug induced parkinsonism (DIP) with hospital populations the highest amount. Some studies indicate 54%. Up to 30% of patients with DIP may develop a persistent or progressive parkinsonian syndrome (PPS). This literally indicate consistent and continuous damage to the dopaminergic systems.

Lets say you grab 1000 patients taking antipsychotic and median of 35% of them get DIP that's roughly 350 patients. 30% of those patients get PPS that's roughly 115. So for each 1000 people taking antipsychotics 115 get chronically ill and develop damage to the dopaminergic system. Roughly 10,5% doesn't recover. I personally think numbers for paliperidone depots are at the highest rate because paliperidone is known to cause DIP. Also hospitals where they force haldol injections would probably have highest percentage of people affected. You don't have to have a high dose or high dosage frequency to develop it.

If you assume 54% DIP rate for paliperidone shots its close to 200 cases with PPS per 1000 taking those shots. That's roughly 20% who doesn't recover at all.

At higher dosages it's accompanied by neuroleptic induced deficit syndrom (NIDS) which is another syndrom that manifest with high dosages of antipsychotics (especially depot shots)


Recovery rates and chances on recovery can probably estimated by observing how many DIP and NIDS symptoms people develop and how severe those particular symptoms are. @dirtyinvega mentioned he developed fullblown parkinsons in high intensity. Another user on youtube (with almost no recovery at year 4) also complained about severe EPS (extrapyramidal symptoms / movement disorders ) and burning pain in the brain (burning brain syndrome). If you don't develop these symptoms including NIDS in high intensity chances are high you're going to (partially or full )recover.

Just my 5 cents
You make a point but I definitely have improved somewhat like the stiffness of muscles at the very beginning I couldn't stand up at all or for very long periods lots of the severe stuff has improved greatly since then but definitely lots of linging stuff just won't improve much now days but at least I can work. ;) I definitely have come a very long way since 7 years ago but damn it's very tiring lol. So not everything is negative definitely not all bad news for me on this journey.
 
So it's impossible to heal from this nightmare.


Negative or positive mindset has nothing to do with healing, you either heal or you don't. Expecting people who are still suffering to be happy against their will is abuse and psychotic.

Again, there's a physical, objective nature to this that the mind can't control. It's not like you can make a cancer go away with this positive thinking nonsense, you gotta have chemo.

Also, baddream, anhedonia isn't psychological, it's a physical condition. I can definetely feel a difference between how i used to be pre-AP and how i'm now. Before then i used to love going to a shopping mall and drink coffe and i remember i'd always feel happy when i'd do it and now when i do it i don't feel anything. No amount of overexerting myself makes me replicate that feeling again, in fact, i don't feel pleasure doing anything and i'm lethargic all the time.
Didnt you say you healed 100%?
 
Does anyone with some recovery have some ability to talk to me? Please I’m really going through it - I’m struggling so hard and feel like I have lost almost all hope and it’s only my first month. Please contact me
 
Does anyone with some recovery have some ability to talk to me? Please I’m really going through it - I’m struggling so hard and feel like I have lost almost all hope and it’s only my first month. Please contact me
Don't lose hope I'm one of the extreme cases and the fact I have two beautiful children now and I am able to work and talk and stand up and tell my story is definitely one of the success stories on this forum I'm telling you! :) I truly believe you are struggling hard I have been there I promise things will improve but baby steps at one given time nothing happens overnight there is always light at the end of the tunnel you just don't see it yet.
 
T
Don't lose hope I'm one of the extreme cases and the fact I have two beautiful children now and I am able to work and talk and stand up and tell my story is definitely one of the success stories on this forum I'm telling you! :) I truly believe you are struggling hard I have been there I promise things will improve but baby steps at one given time nothing happens overnight there is always light at the end of the tunnel you just don't see it yet.
Thanks so much I sent you a dm
 
Actually, I think maybe not masturbating might be beneficial to cisgender men and maybe some trans men since masturbation and sex raises prolactin, and maybe male bodies aren't as good at rebalancing prolactin so they need all the help they can get. But still, try to find a balance between bringing your prolactin down and rebuilding that mind/body connection.

Nofap as a thing is still dumb imo, sorry. It's weird and sex-negative.

Also, men, don't be ashamed of buying a vibrator to help regain sexual function. Wand toys are unisex and there's plenty of other options.
 
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I used to get excited about buying house plants, scented candles, and drinking tea ☺️ the simplest things made me happy. I had a moment today, where I thought about the things that genuinely made me happy. I just don’t do those things anymore:( I’m sure you guys have noticed that you’ve stopped doing things that once made you happy, or am I the only one?
 
I used to get excited about buying house plants, scented candles, and drinking tea ☺️ the simplest things made me happy. I had a moment today, where I thought about the things that genuinely made me happy. I just don’t do those things anymore:( I’m sure you guys have noticed that you’ve stopped doing things that once made you happy, or am I the only one?
Sorry but you need to force yourself to do those things again, you'll eventually find pleasure in it.
 
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