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  • TDS Moderators: AlphaMethylPhenyl | paranoid android

Mental Health Coming off Invega (Paliperidone, Xeplion) injections v 6.0

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roofmaan1 said:
is the problem with dopamine reseptors is that they cant upregulate? do they need time to upregulate?
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your receptors are being antagonized,, spiritually your basically in sheol. You can't receive feel good, reward based, and euphoric messages.

Sarcosine, l tyrosine, and benzos are a superior treatment to schizophrenia.

I'd give Valium and lithium to a stark raving meth head under psychosis over APs.

Worst case scenario a violent psychotic gets a single Haldol pill and xanax.
 
roofmaan1 said:
what if you made your brain super plastic?
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It's brain plasticity and it doesnt do that. Pharma grade meth in LOW
DOSES under a control showed meth could repair brain damage.


There's NO WAY you're getting your hands on pharma grade meth.

Meth has been discussed in this thread long ago. It's not worth it.
 
roofmaan1 said:
is the problem with dopamine reseptors is that they cant upregulate? do they need time to upregulate?
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Endogenous dopamine and most antiparkinsonian drugs exert their actions via postsynaptic dopamine receptors. The two dopamine receptor families (D1- and D2-like) and 5 dopamine receptor subtypes (D1R–D5R) are encoded in humans by 5 genes (DRD1–DRD5).1 In Parkinson's disease (PD), the therapeutic use of dopamine receptor agonists bypasses degenerated mesencephalic dopamine production, but the clinical benefits of agonists are generally less than those with levodopa, and their use can be complicated by various side effects ranging from fibrotic heart disease with ergoline derivatives to impulsive/compulsive disorders.2, 3 There are also results to suggest that long-term and intermittent administration of dopaminergic drugs may cause dopamine receptor downregulation in advanced PD, when response to levodopa is suboptimal and characterized by fluctuations and dyskinesias.4

 
roofmaan1 said:
is the problem with dopamine reseptors is that they cant upregulate? do they need time to upregulate?
Click to expand...
no, there are many problems, including change in receptors shape (which makes them less receptive) and also blockage of receptors by protein binding which can last long. Not to mention that invega does molecular bound with one type of serotonine receptors for mood, that is going to take most time to recover.
 
If you've been newly injected with invega you've entered spiritual sheol
en.wikipedia.org

Sheol - Wikipedia

en.wikipedia.org en.wikipedia.org

Spirituality helps with invega but your
Dopaminergic system is being halted and damaged. Dopamine and serotonin are spiritual currency on earth and invega robs the bank account.

Mushrooms and THC help with this. That plus music can alleviate symptoms and slowly heal the brain.
 
I never leaved the underworld. I’m still on Haldol and need tapering strips.

Everyone talks about me. Places I’ve been, things I’ve bought, things I like.
Like a kid said I like fish. I always like fish as a kid too. Thus this is direct towards me.

What do they want???? Just leave me alone. Never asked to be birthed here anyways.
 
roofmaan1 said:
does anyone have a problem focusing? does focus come back?
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Ya I have problems with this, it feels like invega amplified my ADHD, it’s been steadily improving it should come back as long as you don’t take other APS.
 
Is there any psychedelic that works while on haldol?

I want to trip. The only thing I do is stay in my apartment. I need some action and adrenalin
 
Whathappened123 said:
Is there any psychedelic that works while on haldol?

I want to trip. The only thing I do is stay in my apartment. I need some action and adrenalin
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haldol would probably block psychedelics but it doesn’t do that for everyone, I’d start with low dose mushrooms (1-2g) it sounds like you have psychotic depression, so in that case psychedelics may be able to help but it could also make it worse it’s a gamble but at this point if I was in your situation I’d be willing to try anything, I have weird brain chemistry for me low dose psychedelics calms me down and would make me less psychotic if anything psychedelics get a bad name for some reason just like weed did in 2005, but I feel like we shouldn’t immediately shut the door to the idea that psychedelics might actually help some forms of psychosis for certain individuals.
 
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