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  • BDD Moderators: Keif’ Richards

combing methadone with orlistat (alli / xenical)

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ro4eva

ro4eva

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I've tried searching the forums but came up with nothing.

Has anyone on MMT - who's gained a lot of weight - tried to combine their daily dose with some orlistat 60mg(Alli - OTC) or 120mg(Xenical - Rx), and if yes, how were the side effects of the orlistat when taking into consideration the chronic constipation caused by MMT?
 
Well, I have no experience in this but this link says no interactions, so that's a good start.

I presume you are on medication to help the constipation? Orlistat can cause a lot of gastro-intestinal side effects because you are not absorbing as much fat, which causes steatorrhoea (essentially fatty stools, hah) - this usually leads to diarrhoea due to large, oily, loose stools (sorry to be so graphic hehe) so in theory it could actually help matters! However the decreased fat absorption also causes increased flatus (gas production) which can cause bloating and be really uncomfotable, and an already-slowed-down bowel might exacerbate this, I don't know.

There is nothing inherently dangerous about the combination that I can see but I would check with your doctor, get your constipation as under control as possible then if your doctor thinks it's okay give it a try and see :)
 
You are very pleasant, thank you for your reply.

I'm actually on the medication because I've gained a ton of weight since I started MMT. For the past 6 months, I've been trying to eat healthy and exercise regularly to no avail. In my desperation, I began to spend (waste) money on all sorts of weight loss supplements but I haven't lost any of the weight I've gained - I've only been able to stop the weight gain. I guess you could say I've hit a plateau where my current weight has been consistent for several months now. I then began to think about trying the ECA stack but when I told my doctor she recommended instead orlistat (Rx version - Xenical).

If it does help with constipation that's great, but I'm more interested with the weight loss while on methadone because I tried everything else short of sympathetic stimulants.
 
I have gained 30 pounds while i was on MMT and my dose was 145mg, including massive sugar cravings, sweating, constipation, loss of libido. There are herbs in one that can help with your problem.
 
I realize this might be blog material, however in the interests of helping a fellow bluelighter... I just wanted to let anyone on methadone maintenance who's gained significant weight and/or anyone who's have severe issues with constipation know - orlistat may help you lose weight, and it most likely will make you have regular bowel movements again. Every morning since I've started taking it, I've taken a massively satisfying dump. I don't feel bloated like I used to anyone. In terms of the weight loss, apparently I've lost 3 pounds (I started taking it 5 days ago), but it could be from the regular bowel movements.

Now for the bad news - it's expensive and insurance usually won't cover the Rx version ($180 for a 1 month/90 capsule supply if taken 3x daily) although the OTC version is much cheaper from what I hear (but we don't have it in Canada). Also, I recommend you start off slowly (take just 1 per day) because of the side effects which may include flatulence with an oily discharge (which is undigested/unabsorbed pure fat) as well as mild-moderate cramps when having a bowel movement. You'll be farting a lot, guaranteed.

It's not recreational and it's pricey, but other than having either a blow or meth habit along with your methadone, I find this stuff actually helps with 2 side effects of MMT which I've tried other numerous products for ranging from fiber supplements to natural/synthetic laxatives for the constipation and also ranging from a healthy diet + daily exercise to "ephedra free" weight loss supplements.
 
Thank you for posting an update ro4eva, I'm glad it is working out for you!

I am going to close this thread now but it won't be deleted so others will be able to search and read your report. Any problems shoot me a pm!
 
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