Eh yeh you will feel it but it will be weak imo tolerant or not. There was times back in the day when I had no opiate tolerance and 300-400mg codiene was usually what I would take. It would make me a bit warm, cozy, relaxed, itchy, but I was ALWAYS craving a better high no matter how much I took. Likely cause I had stronger opiates prior that created a stronger frame of reference. But yeh 75mg with no tolerance will do *something, just don't think its going to be anything to get that excited over.