• MDMA &
    Empathogenic
    Drugs

    Welcome Guest!

cocaine

ben2990

ben2990

Bluelighter
Joined
Mar 10, 2010
Messages
512
Location
Dubai
im high on some mdma, everyone on blue light has been telling me it will just block out the mdma high if i snort cocaine wile rolling, but todaya good freind of min told me toherwise, he said it intensifies the hgih and only mkaes it more fun,

i right now, will bust this myth wiide open, and report back my experience:\
 
It's not just a matter of overpowering the roll -- cocaine has affinity to SERT, just like MDMA, except that it just blocks the transporter rather than reversing it. I'm sure there are other reasons, but I imagine that would be a major one for it canceling out a roll.

Thank you for verifying the theory, but sorry to hear about your disappointing experience. :\
 
RGB said:
It's not just a matter of overpowering the roll -- cocaine has affinity to SERT, just like MDMA, except that it just blocks the transporter rather than reversing it. I'm sure there are other reasons, but I imagine that would be a major one for it canceling out a roll.

Thank you for verifying the theory, but sorry to hear about your disappointing experience. :\
Click to expand...

^ This. Cocaine blocks it in the same way as most antidepressants. It blocks the re-uptake of serotonin, noradrenaline, and dopamine, thus blocking the mechanism by which MDMA works. Much better off taking them separately.
 
yeah well maybee i did less damage to m seritonin? or what, cocaine blocks the re-uptake of seritonin, and everything, so tomorrow i should feel less mentally drained or what?
 
ben2990 said:
yeah well maybee i did less damage to m seritonin? or what, cocaine blocks the re-uptake of seritonin, and everything, so tomorrow i should feel less mentally drained or what?
Click to expand...

Good question. Unfortunately, it's almost impossible to say. :\

A few of the factors at work, to give you a taste of why it's hard to answer your question:
  • Cocaine likely does not fully saturate SERT, meaning that the MDMA is still exerting some effect.
  • MDMA has a long half-life in the body, far longer than the duration of its effects. This indicates that MDMA is likely still reversing the transporter long after your roll has ended (and also after the cocaine has been metabolized). It's still a mystery why your roll ends after 5-6 hours even though MDMA's still hanging around -- I personally attribute it to extensive 5-HT receptor downregulation, in which case the cocaine might extend your roll...? It's really hard to say, especially since I'm just an amateur and taking guesses.
  • Doing coke is going to take a toll on your body too, so it's hard to say if you'll feel subjectively "less drained" tomorrow or not.

I wonder if we can get any academic support for a study on the effects of co-administration of cocaine and MDMA...? That'd be a fascinating study, heh. In any case, I would highly recommend against taking cocaine with MDMA to minimize damage...there'd probably be more, since cocaine is strongly dopaminergic. :\

toa$t said:
i don't care what anyone says. I like it.
Click to expand...

8) <3
 
I wouldn't recommend it. I combined the two on NYE. Made my roll from heaven turn into one from hell!! I was on clean rolls too (mints) my heart felt like it was going to explode. Do one or the other, please don't mix them. I'd hate to see someone make the same mistake I did. PLUR!!!
 
SleepingTaper said:
I wouldn't recommend it. I combined the two on NYE. Made my roll from heaven turn into one from hell!! I was on clean rolls too (mints) my heart felt like it was going to explode. Do one or the other, please don't mix them. I'd hate to see someone make the same mistake I did. PLUR!!!
Click to expand...

I also did both for the first time on NYE. The coke was about 7 hours before the rolls with a good 3 hour break inbetween. So we had a really good roll going when we dropped because we took a break from the coke. We had nitrous too so that intensified the roll. We went back to the coke in the comedown. And yes we all felt like massive piles of shit for a week after that LOL So overall it was a great experience for all of us.
 
You must log in or register to reply here.
Top