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  • BDD Moderators: Keif’ Richards

Cocaine Immunity?

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LuvMyZorro

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Feb 12, 2015
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Is it possible to be immune to cocaine? I can take tons of it and not feel anything. I get talkative and wide awake, but I don't feel high at all. I am on Welbutrin and Abilitfy along with a few other meds, do I need to come off these meds for a few days and then try it? do these meds prevent the high? Any thoughts?8)
 
I'm going to take a random stab at this one, but I believe the high from cocaine is the result of it being a dopamine-releasing stimulant, right? And Abilify is an antipsychotic drug which interferes with that process, I'd guess anyway...a lot of people complain that they can't get high while on antipsychotic-class drugs.
 
exactly what occurs for me and I am on antipsychotic and anti depressants which affect it.
 
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Wellbutrin can to some extent block cocaine's effects, as it's also an NDRI, but it causes a comparatively weak effect at relatively high levels of receptor occupancy. However, that you are wide awake and talkative suggests that it's working on you. Cocaine's effects can be deceptively subtle, and not everyone likes it.

This isn't a good basis for a wiki article; please pay attention to where you post next time.

ebola
 
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