cocaine cross tolerance to 6-apb

[sim]

hi everyone.

Friday nights I took about 2 grams of OK cocaine till saturday morning. I plan to take 6-apb thursday or friday night (thursday preferably). Should I expect any tolerance from the cocaine to affect my 6-apb trip in any way??

 

[sim]

bump, somebody must know....

 

[sim]

did I said something wrong or what?

 

[pofacedhoe]

why would there be any?

 

[sim]

edit: you mean why would there be any tolerance left from the cocaine??

i dunno i guess it happens, that's why I'm asking the appaprently mute crowd

 

[Hiltoniano]

No there is no cross tolerance. Cocaine is a DRI. 6apb is a serotonin releaser.

 

[sim]

wiki says:" Biologically, cocaine acts as a serotonin–norepinephrine–dopamine reuptake inhibitor, also known as a triple reuptake inhibitor (TRI)"

and about MDA(wich 6-apb is an analogue) "MDA causes serotonin and dopamine release"

 

[Hiltoniano]

I believe the action on serotonin by cocaine is negligible, and amps and cocaine only have a small crossover tolerance. Wikipedia is not the end all source because it can fail to explain the details necessary to understanding.