• N&PD Moderators: Skorpio

Clobazam and related

clubcard

Bluelighter
Joined
Apr 12, 2013
Messages
1,482
Hi,
I'm prescribed 20mg of clobazam per day for epilepsy and I noted it's almost the only 1,5-benzodiazepine. Board while off sick I went and looked at the patent (US 3836653). They give an example of a 10mg pill which was clobazam with a chlorine at the 2 position of the normally unsubstituted ring (5-(2'-Chlorophenyl)-7-chloro-1H-1,5-benzodiazepine-2,4-(3H,5H)-dione).

is there a reason why 1,5 benzodiazapines are so unexplored (or is it explored but I don't know about it being someone TRYING to learn... so look out in 10 years!).
 
bump, I too, am very interested to see a reply to the OP's question. Has this been explored in any other cases?
 
Top