Leo Zeff, a close friend of Sasha Shulgin and the first psychiatrist to pioneer the use of MDMA for psychotherapy, dosed his patients with 150mg of MDMA (probably Shulgin-made). I'm not sure what the recent experimental research has used as a standard dose, probably more along the lines of 100-120mg (150 seems like a lot, especially for someone who has never taken it before ... and having never taken it before is generally a prerequisite for participating in the research).