Lol, TSD do you work for the board of tourism for the city or something? its cool tho, I love all the museums, reminds me of being a kid, and a nerd, which is always good.
My friend injected dmt after coming off a 3 week dope binge @ 3 or 4 shots per day. he said the trip had a certain amount of "introspective hell" regarding his heroin use, but physically I'd say its pretty safe, in general dmt is pretty safe.
to the original question, in chicago and the burbs, IME LSD is available, but you have to deal with alot of bunk stuff or overpriced stuff, mushrooms are consistently available too but tend to be pricey. As far as 2C-X's go, they are alot more rare, I have met a few people who claim to have connections, but alot of people are all talk. Alot of it is there in the rave scene if you know who to ask. Pure ketamine is around too, but it tends to be damn expensive.