Mr Crowley Bluelighter Joined Sep 26, 2015 Messages 73 Location Under your bed Mar 30, 2016 #1 Do you guys think taking a low dose of bupe would block opiate receptors enough to reduce the sedative effects of dxm and it's metabolites?
Do you guys think taking a low dose of bupe would block opiate receptors enough to reduce the sedative effects of dxm and it's metabolites?
Pilll_head Bluelighter Joined Sep 28, 2011 Messages 466 Location An Altered State Apr 1, 2016 #2 No, it wouldn't have any affect. DXM doesn't use the opioid receptors, I think the tripping is from NMDA receptor and serotonin receptor activity. DXM looks like an opioid but they aren't quite the same.
No, it wouldn't have any affect. DXM doesn't use the opioid receptors, I think the tripping is from NMDA receptor and serotonin receptor activity. DXM looks like an opioid but they aren't quite the same.
zirbeldude2 Bluelighter Joined Nov 13, 2015 Messages 244 Apr 1, 2016 #3 DXM potentiates opioids. But afaik not all of them. It also seems to prevent developing opioid tolerance.
DXM potentiates opioids. But afaik not all of them. It also seems to prevent developing opioid tolerance.