Opioids Cetirizine, Ranitidine & Morphine/Codeine (Poppy Seed Tea) - Need QUICK reply

[ForEverAfter]

I created a new thread for this because I need a really quick response.

I just consumed 20 mg of cetirizine and 300 mg of ranitidine. I was told this combination would reduce itching from the opiates. Planning on drinking a fairly large amount of poppy seed tea in the next half hour. Crimethink warned me:

In mice it potentiated the pain relieving effects and in humans slight increase in respiratory depression (w\ morphine) has been observed at 600mg. Beware.

I assume the 600 mg refers to the ranitidine? I tried googling the combinations, but I don't understand all the scientific mumbo jumbo. It confuses me.

Is ceritizine/ranitidine/morphine/codeine a potentially dangerous combination? Should I go easy on the opiates? I don't have much time to get high because I have to work tomorrow. So I really need a response as fast as possible.

What am I "being wary" of?

 

[ForEverAfter]

Feel fined. Still a bit itchy, though... Is having another ranitidine (making it 600mg) going to do me any harm... or a half (making it 450mg) ??

 

[GABAking]

take benadryl (otc) or hydroxyzine (prescription) for itching. fair superior than cetirizine in my opinion

 

[ForEverAfter]

Okay but is this combo okay? (the one i'm on at the moment...)

I got a really sour - burning - throat about fifteen minutes ago and I'm coughing like crazy. Coughing up shit-loads of lung mucus. I am getting over a bout of pneumonia but I haven't experienced this until just now. My throat suddenly started burning - like way down the back of my throat near my esophagus. And the weird thing is usually you can't cough shit up on opiates. Codeine is a cough suppressant isn't it? Morphine is as well, right? I've tried many times to cough shit up on opiates - due to the badly timed combination of pneumonia and this morphine binge - and found it was impossible. Now, in the past fifteen minutes I've coughed up like a quarter of a cup of shit. I've had more poppy seeds than I normally would; something like a kilogram worth of seed resin.

The coughing fit is dying down now, so I'm not as worried... But it's still a bit weird. If the combination of cetirizine and ranitidine potentiate opiates, then is it possible I came close to an overdose? Is coughing a symptom of an opiate overdose? Or maybe it's a symptom of the combo? Or just the ranitidine?

As for benadryl, I heard that it contributes to feelings of sedation brought on by opiates.. and that the second generation anti-histamines are safer.. still I'm interested to try it.. is benadryl an OTC anti-histamine? When I went in today to get the ranitidine, I told the woman at the counter that I wanted an anti-histamine called ranitidine. Turns out it's not an anti-histamine. She gave me a lot of weird looks. I fumbled with my explanation. Even though the substance has no (?) potential for abuse, it was clear to her and other customers that I was some sort of junky and my reasons for wanting the medication were suspect. Obviously, I'd like to avoid this happening again. So what do I ask for? Is "benadryl" the brand name?

 

[Znegative]

Benadryl (diphenhydramine) is an anti-histamine with IMO no recreational alue. Due to its cholinergic effects it can cause delirium and hallucinations which are often horrifying. However this is only attainable at rather high dosages. While opiates are used as cough suppressants, I've experienced coughing fits and asthma attacks from heroin (though no other opioid does this). I think morphine/codeine can cause suppression of the bronchials in some people and that the mucous buildup is a response to histamine release. I'll have to double check that.

 

[GABAking]

You're slightly misinformed, but on the right track. here's what i gotta say...

Yes, benadryl is over the counter. its generic name is diphenhydramine. Ask any pharmacist and they'll direct you to it. it's very effective at treating allergies and itching, as well as potentiating the sedation accompanied by opioids. it's an antihistamine

Ranitidine is used to treat gastric reflux and ulcers. it's also an antihistamine, but it does not help allergies (at least for me). in the body, histamine stimulates gastric cells to make/secrete hydrochloric acid. i've never heard of it potentiating opiates, but my best guess is that this medication will raise your stomach pH (less acidic), so the tea doesn't break down as quickly.

your coughing...honestly i don't know. opiates, in particular codeine, are very effective cough suppresants, but my guess is you're coughing 'cause you were recently sick.

now is it safe? in my opinion yes. because every day i take ranitidine for GERD, both cetirizine and hydroxyzine (which is basically benadryl, you just need a prescription for it and it's much better at potentiation) for allergies, and i use a lot of opiates. i'm prescribed percocet and my doctor knows all the meds i'm on so he saw no inherent danger. i also use heroin, dilaudid, oxymorphone, morphine--you name it...and i've never had any problems


if you have any more questions shoot me a private message!

 

[ForEverAfter]

I'm taking ranitidine with cetirizine to reduce the itch. I know that ranitidine isn't an anti-histamine. I didn't know that when I bought it, I was just going on the advice of Crimethink - the bluelighter who recommended I try it. I've since deleted the thread, which contained a link to the study about ranitidine and cetirizine to treat itching. Although ranitidine is used to treat stomach conditions, it is a histamine H2-receptor antagonist. And cetirizine is a histamine H1-receptor antagonist... whatever all that means. The combination is much more effective in terms of treating itchiness than taking cetirizine alone. I specifically didn't want a histamine/itch fix that increased/potentiated the effects of the opiates - which is why I chose this combo rather than benadryl for the time being. Though i'm starting to itch again now. I think next time I'll try benadryl and see how that goes. Morphine would be awesome if it wasn't for the damn itchiness.

I appreciate your comments GABAking and Znegative. I've stopped coughing now. Probably just something to do with the pneumonia. I tend to not notice the temperature when I'm on opiates, which is not good for my chest infection. I need to make sure I keep warm.