Casual marijuana use linked to brain changes

slimvictor

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"Darkness cannot be dissipated with more darkness.
A new study links casual marijuana use with significant changes to parts of the brain.

Using marijuana a few times a week is enough to physically alter critical brain structures, according to a new study published Tuesday in The Journal of Neuroscience.

"Just casual use appears to create changes in the brain in areas you don't want to change," said Hans Breiter, a psychiatrist and mathematician at the Northwestern University Feinberg School of Medicine in Chicago, who led the new study.

There is actually very little research on the potential benefits and downsides of casual marijuana smoking — fewer than four times a week on average.

In his study, done in collaboration with researchers at Harvard University, scientists looked at the brains of 20 relatively light marijuana users and 20 people who did not use it at all. All 40 were college students in the Boston area.

The study found volume, shape and density changes in two crucial brain areas — the nucleus accumbens and the amygdala — involved with emotion and motivation and some types of mental illness. "This is a part of the brain you do not want to mess around with," Breiter said.

The more marijuana the students smoked, the more their brains differed from the non-users, the study found.

The brain continues to develop well into the 20s, and even into the 30s, said Breiter, who is concerned about the long-term impacts of marijuana use on the developing brain.

Staci Gruber, an associate professor of psychiatry at Harvard Medical School, who was not involved in the research, said Breiter's findings are consistent with her own, although she has focused on somewhat heavier users.

"There have been a growing number of studies that suggest that marijuana use in emerging adults is associated with differences in brain structure and cognitive abilities," said Gruber, also the director of Cognitive and Clinical Neuroimaging Core at McLean Hospital outside Boston. "I'm not saying (pot smoking) is analogous to shooting heroin or cocaine, but it's also not quite the benign substance people thought it was."

(…)


Gregory Gerdeman, a biologist and neuropharmacologist at Eckerd College in St. Petersburg, Fla., said he has no reason to doubt the new study's findings but worries generally about marijuana research funded by federal agencies, like the Office of National Drug Control Policy, which is charged with limiting drug use. (The research was supported by grants from the National Institutes of Health as well as the Office of National Drug Control Policy and Northwestern Medicine's Warren Wright Adolescent Center.)

"If you're getting money from the drug czar's office, that money's not going to continue if you don't end up publishing something that at least supports the general story of the danger of drug abuse," Gerdeman said.

He said it doesn't surprise him that heavy pot smoking might make it difficult for students to reach their intellectual potential. But still, he said, "if it were my child, even with this study, I'm more comfortable with young people having a casual marijuana habit than drinking regularly."

full article at
http://www.usatoday.com/story/news/nation/2014/04/15/marijuana-brain-changes/7749309/
 
The 20 pot users in the study, ages 18 to 25, said they smoked marijuana an average of about four days a week, for an average total of about 11 joints. Half of them smoked fewer than six joints a week. Researchers scanned their brains and compared the results to those of 20 non-users who were matched for age, sex and other traits.

The results showed differences in two brain areas associated with emotion and motivation — the amygdala and the nucleus accumbens. Users showed higher density than non-users, as well as differences in shape of those areas. Both differences were more pronounced in those who reported smoking more marijuana.

Volkow said larger studies are needed to explore whether casual to moderate marijuana use really does cause anatomical brain changes, and if so, whether that leads to any impairment.

The current work doesn’t determine whether casual to moderate marijuana use is harmful to the brain, she said.

http://www.washingtonpost.com/natio...caabac-c4db-11e3-9ee7-02c1e10a03f0_story.html
 
Half of the group said they used marijuana at least once a week, and the other 20 had not used the drug in the past year, and reported using it less than five times in their life.

Among the group that did smoke, the median use was about six joints per week.

Scans revealed that the nucleus accumbens was larger in marijuana users, compared to non-users, and its alteration was directly related to how many joints the person used. The nucleus accumbens is a hub in the brain that is involved with decision making. Structural changes were also seen in the amygdala.

These changes, Gilman said, may be evidence that the brain is forming new connections that encourage further drug use, “a sort of drug learning process.”

The results are similar to animal studies that show when rats are given THC, the mind-altering ingredient in marijuana, their brains also form new connections, indicating an adaptation to the unnatural level of reward and stimulation from marijuana.

Other scientists not involved in the study say it’s small size makes it hard to extrapolate to the general population. But they also say the findings may help explain what’s happening to the brain of participants in other marijuana studies that demonstrated behavioral and functional changes, but did not use scans to match potential brain abnormalities.

(…)

Dr. Hans Breiter, a co-author of the Mass General study, said there are still many unanswered questions about the potential long-term effects of these various chemicals, especially if people use more than one drug. One of his earlier studies, for instance, showed that the amygdala region of the brain shrunk with cocaine use, while the new marijuana study suggests an increase.

http://www.bostonglobe.com/lifestyl...eport-shows/X1cN8A7h5pOVJkeYkXTXlJ/story.html
 
Interesting, although tbh I didn't read all of that 8)

Anyways I just wanted to mention something about the brain: Our neurochemistry is always changing, the brain is in constant flux. It changes based on, for instance, whether you consume something with a lot of sugar (they suggest you have a steady glucose level, not a low one, when you have to discuss something possibly stressful for a reason, so you're able to stay reasonable and your thought process doesn't go all haywire as it tends to do when you get into a heated argument when you haven't eaten in a long time or are just hungry). If you haven't eaten in a while, and are very hungry, you brain is different than when you have just eat a significant meal and feel full.

You brain changes after you smoke a joint, or after you get a shot of morphine. But, like food, it doesn't permanently change you brain in some horrible dramatic way. Cannabis and opiates are some of the safest drugs out there on you body.

Granted, long term use will change your brain in a more permanent way, but this doesn't mean DANGER DANGER you're FUCKED up... Does this make sense?

The brain is a very powerful organ, can heal itself very well, if one only gives it the chance and is good to it giving it rest (sleep), nourishment (food) and love (we're social animals). It can def (re)achieve homeostasis, regardless of how many morphine or joints you've taken. And frankly I just don't buy the whole uniqueness theory related to powerful opioids like heroin. And opioid is an opioid, at the end of the day.

So the point is, when it comes to the brain (and most other things, if not all things), change itself is neither abnormal nor bad. The question is what qualified as "significant" change.

Furthermore, it is important to know if this significant change should actually be considered harmful, as the brain changes (a LOT) from birth to the age 25, much more than the use of most drug, even using them for loooong periods of time.
 
That's a small number of people for a study. Your brain changes even when you drink caffeine, drink alcohol, or if you use nicotine, a medication, or if you meditate, exercise, and from lack of exercise.
 
UK - Even casual use of cannabis alters brain, warn scientists

Telegraph

By Rebecca Smith, Medical Editor
10:03PM BST 15 Apr 2014

With reader comments

People who had used cannabis once or twice a week for a matter of months found to have changes in the brain that govern emotion, motivation and addiction. Experimenting with cannabis on a casual basis damages the brain permanently, research has found. It is far from being a “safe” drug and no one under the age of 30 should ever use it, experts said. People who had only used cannabis once or twice a week for a matter of months were found to have changes in the brain that govern emotion, motivation and addiction. Researchers from Harvard Medical School in America carried out detailed 3D scans on the brains of students who used cannabis casually and were not addicted and compared them with those who had never used it.

Two major sections of the brain were found to be affected.

More...
http://www.telegraph.co.uk/health/h...of-cannabis-alters-brain-warn-scientists.html
 
I wonder how much regular use of TV changes your brain. I bet its even bigger when you watch a bunch of Fox news.

Come to think of it I bet carrying out a study like this changed their brains.. we need to study how studies change the brain.
 
The article reads to me like someone somewhere is doing too much cannabis. It is known to cause paranoia. Drug tests all around.
 
spelling

what is it with the media slating (taking the piss out of) cannabis use at the moment. Its really weird. especially in the UK. Ever since they started getting less strict in other countries, i find it all very odd. I dunno why or who's idea it was but it makes me sad :( it looks like other countries are starting to get a little less ridiculous when it comes to weed use as well; legalising/decriminalisation and medicinal use are all standard practice in a lot of countries now but articles like this seem to be appearing out of the UK more than they were before. Also i think the fact that its still a class b is very odd/annoying. it just seems weird/wrong that cannabis is a class b and yet benzos and other drugs that can actually be VERY harmful are all class C (ketamine, i think is a class c or at least it was when i was last raided by the police.). Very strange if u ask me, when are they gonna let us who have mental health issues or for that matter even terminal patients, et scripted weed!? I don't like to be pessimistic but i just don't see it happening here in the UK for a long while. I say bring it on!
 
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Such grotesque propaganda under a thin veneer of science. They are using the old tactic of pretending change is damage. Anything that stimulates the brain in any way changes it. Anything someone enjoys will change the brain in the way they speak of. If someone is motivated to do ANYTHING that they like the same parts of the brain will be changed. I hate how they alter words like damage until they become meaningless propaganda buzz words.
 
Well put opiamp, people love to hide their (prejudiced) ideas behind science. Fucking insidious iyam

I wonder how much regular use of TV changes your brain. I bet its even bigger when you watch a bunch of Fox news.

Come to think of it I bet carrying out a study like this changed their brains.. we need to study how studies change the brain.

YES! Using tablet, smart phones, computers and TV is demonstrated to alter the brain, ESPECIALLY in children who are using these devices more and more. Instead of going to bed and getting rest they stay up for four hours after bed time because they can hide their tablet or phone under the covers and play games all night. Night after night, you can see how this could mess with their brain chemistry/development big time.
 
This is a more detailed repost of a thread that was just posted. Why no merge?

It is more propaganda bullshit where they pretend any change in your brain is permanent damage. As I said in the other thread doing anything changes your brain as it is plastic and changes with experience. More lies under a thin veil of science.
 
I appreciate all discourse on the subject of drugs use & the possible dangers thereof, even outright paranoid rants from pale, internet folk who rarely see natural light or communicate vocally... & the more outrageous the better, because it illustrates the desperation felt by those against liberalising the globes drugs laws. It's nice to see the enemy feeling as desperate as I've felt for the last 25 years or so.

But if a study of 20 SSRI users showed that, compared to 20 non-SSRI-users, they all had permanent brain changes after using SSRI's for a year or two the results would likely never be published because the sample would be deemed too small to have any significance. If the results were still publised they would be published alng with the caveat that the sample was very small & the results not likely to be relevant.
 
edit- Telegraph link functions not for me!

Listening to music causes changes in the brain for Gods sake. Perhaps these silly stoners listened to Guns n Roses stoned or something. I for one would never be the same!

There should be a warning on all media, "you may change your mind, (ie permanently alter your brains wiring system) simply by listening to or watching this material". Especially if you do it stoned.

Kinda makes sense really. I've seen things on TV that have permanently affected me emotionally, if that is not an indication of re-wiring of the brain by media, what is?
 
Neuroleptic antipsychotics shrink the brain directly through atrophy and lead to permanent movement disorders like tardive dyskinesia from the brain damage they cause.
 
LoL What kind of nonsense bullshit study was this supposed to be?? The people involved in this study should be fired and put into a retarded house so they can babble retarded nonsense to each other all day and not infect the rest of civilization.
 
“Drug abuse can cause more dopamine release than natural rewards like food, sex and social interaction. That is why drugs take on so much salience, and everything else loses its importance.” The study is published in the Journal of Neurosciences.

You know I'm getting tired of hearing this absolutely untrue statement. After decades of use and abuse of many drugs why is this not true for me. I find more pleasure and importance in life now than i ever have. A factual way to state this would be that the brain keeps track of dopamine releases and ranks them n order of magnitude and how rapid they are. Everything needed to sustain life is associated with a drive to accomplish it and when it is accomplished we receive the dopamine. When we use drugs the related dopamine release is logged into this this system and we risk the use of the drug being tagged with its own drive. If and when the use of a drug is given a drive then we have addiction. Could this become our number one drive for awhile, sure I bet it could. Is this a permanent sate, no way.

If we think about this system and a few of the natural drives we can see that the power and frequency of drives is a varying phenomenon. It can increase and decrease. Think about the sex drive of a teenager, its through the roof, but if we fast forward to when they are forty five years old it would be really unusual for that person to have the same sex drive that they had as a teenager. Many people and animals experience much stronger hunger drives associated with the seasons and find them self being strongly driven to consume food as winter approaches. If a person is low on fluids they will find that their thirst drive greatly increases.

Can an addict have the use of their DOC as an obsessive drive above all else for a period. Yes, but this is not a permanent state. Is it possible to consciously change these drives. absolutely, other wise what happens when a person trades on addiction for another. Can a person consciously effect this system.. absolutely. We hear of or witness people doing this frequently. A story like an executive who quits their job to go work for green peace.. After spending twenty years obsessively and compulsively working as much as possible to get as much money as possible to by as much stuff as possible they looked around at all their material garbage and realized they needed something something different. So they quit their job, sold their garbage, and went to save the whales. This certainly indicates a change in this system. When once they likely received a big shot dopamine when they looked at how much their bank account was worth and how big their house was they probably no longer received this anymore. How did they come to this realization and resultant change in drives.. I would assume it came from altering their values with conscious thought.

When you listen to music, much more is happening in your body than simple auditory processing. Music triggers activity in the nucleus accumbens, a part of your brain that releases the feel-good chemical dopamine and is involved in forming expectations.

At the same time, the amygdala, which is involved in processing emotion, and the prefrontal cortex, which makes possible abstract decision-making, are also activated, according to new research published in the journal Science.1
Why Your Brain Craves Music

If you dont want to cause "damage" to these areas of the brain then you will need to refrain from all pleasurable activity. Like I always say, stay in your house and drink filtered room temperature tap water and raw vegetables. By doing this you be the safest, live the longest, and cause the least amount of "damage" to your brain.
 
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