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Carnival of psychedelic poultry- PD Silly Goose make out session

Set the gearshift for the high gear of your soul!!!!!!!!!!!

listening naow

With bose headphones, as prescribed.

Didn't even notice this is an '87 show...=D
 
I think I have found a new "top 3" 'lopes. Number one being 10/31/94. favorite phish show ever actually, minus the white album cover...not that it wasn't sick though.

EDIT: I don't know my way around nugs, but if you can find the reba from 10/31/94 give it a listen, I am starting a religion upon this recording.

EDIT2: Golgi as well8o
 
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IGNVS said:
did even more reading. on resveratrol. looks like the trimethoxy version (looks alot like mescaline) is actually cancer preventing and killing. http://carcin.oxfordjournals.org/cgi/content/full/22/2/321
Click to expand...

That's cool man. I've read in more than one place about certain cactus alkaloids from psychoactive cacti having anti-cancer properties. Wouldn't be surprised if variations of mescaline have that property, heck maybe even mescaline itself. :)
 
im trying to figure out what the mescaline version of resveratrol would be lol

imagine a 5 carbon ring around the amine of mescaline with a hydroxy group sticking out across from the nitrogen

wuzzat called?

n-(3,4,5-trimethoxyphenethyl)-4-hydroxypiperidine (dunno if thats how you would name what im thinking of)

too much chemistry... time to smoke a bowl
 
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yeah it would (you can only make 3 bonds), and i supose that plays a role in the pharmacology of it all dont it?

well, there are mescaline analogs found in peyote ( the malemide version of what i posted)that have the same kind of thing going on... dunno if they are active.
 
This is my favorite mescaline analogue:

mescanalog.png


Any of you chemist-to-be:s, please synth this (and send me a sample)! ;)
 
dread said:
But that's not a phenethylamine, that's a phenethenylamine...
Click to expand...

yeah i noticed that, i was just about to post in add about those to see if they are psychoactive. in the compound i wanted to keep as much of the MR-4 (resrevatrol analog) molecule in tact as posible

that is a favorite of mine too! instead of the 4 ring i like the 5 ringed version that attaches from the beta to the 2 position though (never tried it, just looks more aesthetic.) and i never thought about having a triflouromethoxy group (just throught of trifloroethyl, but the oxygen would definatly add to the electron density in that area).

i like all these ideas people are having.
 
Personally when it comes to extra rings and all that kind of funky stuff, I'm interested in aminorex versions of things. I recently got the idea from a certain picture of a blackboard in a certain recently deleted thread. It had 3,4-methylenedioxyaminorex on it, curious what that one would be like. Also maybe 3,4,5-trimethoxyaminorex (I'd call it "mescalinorex" :D)

here's the basic aminorex backbone:
220px-Aminorex-2D-skeletal.png
 
The problem with applying the substitutions of psychedelic phenethylamines to aminorex is that aminorex is not a phenethylamine, it's a phenethylimine. With an extra amine and cyclic structure... I think it would be active, but very likely not psychedelic.

ps. quick SAR predictions on the activity of mescaline analogs...

trifluoromescaline: 20x mescaline (2c-d active at 20mg, 2c-tfm active at 1mg, switching methyl to trifluoromethyl = 20x potency increase)

mescaline w/ benzocyclobutyl ring structure: 20x mescaline potency (2cb active at 10mg, tcb-2 active at br-dfly dosages - I assume this means around 0,5mg, adding cyclobutyl structure to 2cb = 20x potency increase)

The compound I drew, trifluoromescaline w/ benzocyclobutyl ring structure, would have both of these 20x potentiations combined, so one could predict it to be 400x more potent than mescaline. How convenient: 1mg would give you an equivalent dosage of 400mg mescaline...

How cool would that be?
 
HA!! Just found a thread about the blackboard chem in ADD. :) Perhaps we should take these discussions over there maybe?

I realize those pictures weren't supposed to be posted but they've already leaked, might as well be used for chemistry conversation fodder.
 
Its days like this I wish I could attach myself to a coathanger and just like hang and stuff.


Yeh, one of them. A coathanger day.
 
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