I think that is possible, though I think it's down a lot of different variables. I haven't seen it happen so much with LSD or shrooms, but with something like 25I, which in my experience is much more intrusive, then I can definitely see this kind of thing happening. There are just moments in trips where people can become convinced of almost anything, and be unable to detach themselves from that, so if it's something negative from which they try to hide, it can really come back to bite them, or indeed take over the trip entirely. Like I said though, I think it's very much down to many different variables, like the persons' own experiences and mental strength, as well as the dose taken and the specific psychedelic itself. I have certainly seen some crazy irrational stuff happening before where people forget they are tripping at all from 25I overdoses, but I've also seen it happen once to somebody who had taken LSD. IMO there are lots of variables involved that extend beyond the drug itself, though with drugs that are sufficiently intrusive (like 25I at high doses), then some people may just cave in and be dominated by a negative experience.