The 2cs are like mescaline's inferior little brothers.
It has nothing to do with being illegal (the 2cs are illegal here anyway, whilst mescaline has legal options) or natural, since I don't buy into the natural vs. synthetic thing at all.
Better euphoria, much less bodyload, lovely visuals, comforting, humbling. Lovely stuff.
Just for the sake of things, I've done 2c-b, 2c-bFLY (ok, not really a 2c), 2c-i, 2c-e, 2c-t-7 & 2c-t-2.
Out of those I think 2c-b is the only worthwhile one.