Just wanted to add my two cents -
I am prescribed bupropion long term (2-0-0 of generic 150mg XR), however when I was studying at uni (MD program, I failed) I would crush and snort, or smoke bupropion on foil, as a sort of pick-me-up and stimulant to hopefully pull me through. Especially once I ran off of 4f-mph and later 2-fma.
I cannot attest to any of its seizure activity (per studies it's true, but I haven't experienced any seizure on bupropion and in my whole drug-abuse journey there is maybe one or two suspect cases in which I am unsure - both were 2+g of NEP vaped <4h) however I can confirm it's snortable, though it hurts as hell (there's no RC that I tried that burns even remotely close to crushed bupropion, it really feels like snorting concentrated acetic acid but without the smell, it's very deep, sharp, stabbing sensation) and it provides minimal stimulation. At one point the stimulation is just paranoia keeping you awake. As if you're tired and want to sleep but are so afraid of something you don't know what that you're just awake shaking.
Bupropion has been a very good medication for me in prescribed dosage (300mg), but it's definitely not recreational or fun drug. Especially as I suspect its nAchR antagonism can prove delirious in nature, as showcased by fellow trndvd.
When I smoked I would crush the tablets, toss them into water right before boiling-point, take it off heat, keep mixing, once it would get from hot to warm so I would not burn my hands I'd filter through coffee filter, then boil off the excess water from the filtrate, leaving with small, needle-like crystals. From an arm's length it looked like uniform white powder.
There was most likely a huge amount of bupropion lost due to bupropion's low solulability in water, which I realized and sometimes ate the sludge to recoup some of it. However first-pass metabolism changes bupropion's pharmacology too much to be really abusable.
Then it was just the classical chasing the dragon on foil. I don't remember the taste anymore, don't really remember much from that time anyhow. Also the effects when smoked are non-remarkable. It's the same as IN, just quicker, messier and more disgusting. I hate to what lengths I went to attempt to cure this despicable, end-worthy shitplace called World.