Stimulants Buproprion smoking

[TheGyattDamnRizzler]

I know there was a fad for shooting wellbutrin at one point. I can't judge but that's pretty heinous, does wellbutrin even get you high?

 

[nato23]

I’m in the UK and doctors just WILL NOT prescribe me bupropion, they just keep throwing SSRIs at me when i am 95% that its low dopamine that’s causing my anhedonia, anxiety&depression and PTSD.
I’ve had to resort to searching for a illegal source of it, which is bupropion hydrochloride - thank god I found her because this stuff fucking works!

 

[headshrinker89]

I know there was a fad for shooting wellbutrin at one point. I can't judge but that's pretty heinous, does wellbutrin even get you high?

I was totally surprised by the great rush it triggers, considering it's an antidepressant. But the high is very short-lived (5–10 minutes), followed by an incredibly annoying phase of agitation or anxiety. That’s when you want to use it again; this shit is compulsive. It permanently messed up some of my veins.

 

[4DQSAR]

I’m in the UK and doctors just WILL NOT prescribe me bupropion, they just keep throwing SSRIs at me when i am 95% that its low dopamine that’s causing my anhedonia, anxiety&depression and PTSD.
I’ve had to resort to searching for a illegal source of it, which is bupropion hydrochloride - thank god I found her because this stuff fucking works!

In the UK the ONLY Zyban (bupropion) indication in the BNF is 'To aid smoking cessation in combination with motivational support in nicotine-dependent patients'.

So clinicians quite rightly WILL NOT.

IF you ask to be referred to a psychiatrist who has experience using the medication off-label then maybe, but the only dose-form in the UK is the 150mg SR formulation which means there just isn't the scope to titrate the dose to the patient which is important in the treatment of unipolar depression. Yes, a compounding pharmacy could provide other formulations but not on the NHS i.e. the patient would likely have to pay whatever the compounding pharmacy charges.

In The Medicines Act 1986 the term 'specials' is used but the point is that any special formulation hasn't been through the same battery of tests that standard formulations have been through. In essence it becomes 'personalized medicine'.

I guess it you really feel you need it, it may be worth asking. But it may be worth your time first locating psychiatrists who have experience with the medication as no clinician is happy prescribing a medication they are unfamiliar with, especially off-licence.

.

 

[Nepovalerone]

In the UK the ONLY Zyban (bupropion) indication in the BNF is 'To aid smoking cessation in combination with motivational support in nicotine-dependent patients'.

So clinicians quite rightly WILL NOT.

IF you ask to be referred to a psychiatrist who has experience using the medication off-label then maybe, but the only dose-form in the UK is the 150mg SR formulation which means there just isn't the scope to titrate the dose to the patient which is important in the treatment of unipolar depression. Yes, a compounding pharmacy could provide other formulations but not on the NHS i.e. the patient would likely have to pay whatever the compounding pharmacy charges.

In The Medicines Act 1986 the term 'specials' is used but the point is that any special formulation hasn't been through the same battery of tests that standard formulations have been through. In essence it becomes 'personalized medicine'.

I guess it you really feel you need it, it may be worth asking. But it may be worth your time first locating psychiatrists who have experience with the medication as no clinician is happy prescribing a medication they are unfamiliar with, especially off-licence.

.

The way nato23 talks about acquiring it also suggests he has bupropion as an API, which is probably even worse than the SR formulation as there are no excipients that can guarantee homogenous (or even predictable) release of the drug.

At this point I'd too side with medical professionals, maybe not on SSRIs specifically but on atypical serotoninergics or SNRIs.

 

[notsmokeymcpot42088]

lol here in the states if you have "Tried more than 2 antidepressants" you qualify for esketamine -- which I hear isnt much but kinda funny by comparison

I urge everyone here not to abuse buproprion for fun. Dont you damn kids get ritalin anymore?? You probably arent kids so that doesnt apply, sorry. Theres gotta be something better though

 

[4DQSAR]

The danger of using ANY unprescribed medication is IF something goes wrong, either you are honest with your clinician but the bond of trust is lost or you hide the fact and your clinician might make the wrong diagnosis.

I am of the opinion all well informed adults should be able to legally and openly buy whatever medicines they want for their own consumption but sadly that 'well informed part' is so hard to measure.

I don't think a little black box on the packaging of hydromorphone ampoules warning of overdose and potential addiction are quite enough.

 

[Nepovalerone]

lol here in the states if you have "Tried more than 2 antidepressants" you qualify for esketamine -- which I hear isnt much but kinda funny by comparison

I urge everyone here not to abuse buproprion for fun. Dont you damn kids get ritalin anymore?? You probably arent kids so that doesnt apply, sorry. Theres gotta be something better though

Depends on country, when we're talking EU, but here stimulants can be legally prescribed only to children.

The moment you turn 18 you get forcefully switched to atomoxetine, or if you're extremely lucky - bupropion.

It was a huge thing when lisdex got approved here and more than 1/2 of physicians are still pissed about it, claiming abuse rates will soar and it "won't help ADHD kids anyhow"

 

[notsmokeymcpot42088]

I did not know that... Here in the us (in the 90s) most the kids that grew up on ritalin just got switched to adderall when they hit 18! Now I think it is less prevalent but still pretty normal.

pretty tight with the stimulants for adults --- but for kids it is okay? Think I saw a study that said you are pretty significantly more likely to have heart problems you scripted that ish as a kid for years and thought "Well yea, you didnt see that coming!?"

 

[Nepovalerone]

I did not know that... Here in the us (in the 90s) most the kids that grew up on ritalin just got switched to adderall when they hit 18! Now I think it is less prevalent but still pretty normal.

pretty tight with the stimulants for adults --- but for kids it is okay? Think I saw a study that said you are pretty significantly more likely to have heart problems you scripted that ish as a kid for years and thought "Well yea, you didnt see that coming!?"

I believe the evidence for stimulants being curative - meaning actually curing the underlying neuropsychiatric cause, is more rigid for children and that's the whole logic behind it here. But it's been a long time I've been out of the medical-professional field (something between 3 and 4 years since I dropped out, can't be bothered to count it)

I agree with stimulants having the greatest benefit in children, and in most children I'd deem the stimulant -> cardiovascular link to be well worth it, but it's quite horrible for us adults who actually do need the stims because the only way you can obtain stims will sooner or later entice you to just YOLO it and rail lines.

But once enough time passes you get over it and just hope a train smacks you one day when you forget to look at the railway barrier lights.

 

[notsmokeymcpot42088]

I am not going to argue that it isn't not curative cuz I have no M.D to back me --- shit does cause cardiovascular problems down the line (For some) though.

The whole medical community needs to loosen up, id rather have someone railing adderall than jumpin into a train --- or more likely turning to meth its cheap ugly cousin and than dosing it at like 10x therapeautic values minimum.

Let the ppl olo they way they want. Personally im glad I wasnt put on ritalin as I know it woulda got me into trouble...thats just me though.