Correct me if I'm wrong, but I believe Wellbutrin can take a number of days to build in your system and take effect, meaning you would have to preemptively start taking it in order for it to be of any benefit. If it works for you (and antidepressants have variable effects from person to person), it might be useful in enhancing your mood, especially during PAWS, but I doubt it would really do much for your acute withdrawal symptoms. Wellbutrin is known to lower the seizure threshold, so it should not be taken for alcohol or benzo withdrawal. For opiate and especially methamphetamine withdrawal (especially in the later stages), however, it seems like it may be useful.