Buprenorphine Half-life and Elimination

[Hatious]

So I took 24 this Friday and then 32mg the next day.

I'm wondering if the total amount will be eliminated at the same rate. Like my 24mg dose has a half life of 37 hours. Does my second dose of 32 have a separate rate of elimination or does the entire amount in my body get eliminated at the same rate? I figured that I'm looking at about 188 hours until it's basically or near eliminated. I'm wondering if my second dose has its own elimination rate.

Does that make sense?

Thanks.

 

[laCster]

The doses just add on. You will probably be out of withdrawals for 36-48hrs in me experience.

Half life doesn't directly correlate with the duration of the effects of the drug. Again, you will probably be good for 36-48hrs after your last dose, but after that you will need to redose.

Why are you taking so much suboxone ? The ceiling is at around 6-8mgs, any more and you don't increase the effects, just the duration of action. I had a pretty hefty opiate tolerance and I was held by 1-2mgs of bup a day. I find that I feel much better at these low doses, it feels more like a full agonist at 1-2mgs because of the main metabolite norbuprenorphine being a full agonist and at low doses the bup doesn't fully saturate the receptors leaving room for norbup to bind to receptors