Bromide salts as sedatives

[Limpet_Chicken]

KBr and NaBr were, in rather older times than we are now, used as sedatives, I am fully aware they are not at all recreational, but how efficient, compared to say, promethazine, diphenhydramine, etc, or benzos are they as sleep aids?

Do they have any tranquillising/relaxant (again, not recreationally, but purely physiologically) effects? the reason I'm asking, is because normally, I ALWAYS feel jittery, I cannot take sympathomimetics suchas ephedrine (not for abuse purposes, but for nasal decongestion), and very rarely take amphetamine/meth/ethylamphetamine for this reason, so I am attempting to find some sort of rotating schedule so that I am never without some sort of drug to reverse this.

I was thinking something along the lines of rotating a low dosage of an opiate (either morphine or dihydrocodeine), a benzo (nitrazepam), and a sedative antihistamine (promethazine), and hopefully, a few other classes of downers, with dissimilar modes of action, so as to avert feeling like I am permanently tweaked out.

Funny enough, the stimulant 2-aminoindan which I have been currently trialing, seems to help, but after insufflating 2x 50mg over a single day, once in the morning and once in the mid-afternoon, I ended up taking 50mg nitrazepam and 25mg promethazine, and still being fully alert and wide awake, when normally 10mg would have me sleeping properly.

Alcohol is out of the question, as I both dislike drinking, and it hepatotoxic effect, GBL is alright for low-dose occasional use, but again, like benzos, its a GABA agonist, and I have, due both to natural tolerance, and former addiction, a pretty hefty tolerance to GBL/GHB that makes it unsuitable for sleep, but alright once in a while recreationally, as the dose I have to take to induce sleep causes the dopaminergic rebound effect and wakes me up, needing a further dose, and I have NO desire to go through acute GBL withdrawal again, ever

So, would including bromides perhaps help, as I wish to build a tolerance to none, but gain the effects of any, on a rotating basis.

What sort of dosage with the bromides are we talking? as I have easy access to any grade, from ACS to pool cleaning NaBr and KBr.

 

[Smyth]

http://en.wikipedia.org/wiki/Potassium_bromide
http://jnnp.bmjjournals.com/cgi/content/full/72/3/412

All I can say is, you could try it. I personally would not touch it without having researched it. Next, maybe you'll want to try lithium carbonate? good luck with it

 

[jasoncrest]

There is a sedative drug containing bromide still commmercialzized where I live.
From what I read, it works through GABA-A receptors (like benzos and zolpidem/zopiclone/zaleplon).
However I never tried it, because it is potentially toxic (it can cause neuropsychic troubles and other things...)

 

[Limpet_Chicken]

Smyth, thanks for the links, I think I will pass on the bromides, lol, lithium carbonate, heh, insomniac I am, but manic depressive? nope, just manic

 

[DexterMeth]

"The drug has a complete bioavailability and an extremely long halflife of 6 weeks"
jesus f'ing christ

Loss of appetite, nausea/emesis, lethargy, propensity to sleep during daytime, depression, loss of concentration and memory, confusion, headache, bromism (central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia (abnormalitities of gait), loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, frank delirium, aggressivity, psychoses) as well as acne-form dermatitis and other forms of skin disease and mucous hypersecretion in the lungs. Asthma bronchiale and rhinitis may worsen. Rarely, tongue disorder, aphten, bad breath, obstipation, diarrhoe, loss of body weight, bromoderma tuberosum, panniculitis, Very rarely: gastritis, gastrointestinal ulceration. Pancreatitis my also be encountered in exceptional cases, but can be severe or even fatal. Hyperkalema with gastric intolerance and diarrhoe is also possible. Hypothyreosis and arthritis have been seen.