Ketamine Blixeprodil

[Smyth2]

Blixeprodil
(2R)-2-(4-Fluorophenyl)-2-(methylamino)cyclohexan-1-one
GM-1020 or as (R)-4-fluorodeschloroketamine ((R)-4-FDCK),
[2881017-49-6]

Klein AK, Austin EW, Cunningham MJ, Dvorak D, Gatti S, Hulls SK, Kiss L, Kruegel AC, Marek GJ, Papp M, Sporn J, Hughes ZA. GM-1020: a novel, orally bioavailable NMDA receptor antagonist with rapid and robust antidepressant-like effects at well-tolerated doses in rodents. Neuropsychopharmacology. 2024 May;49(6):905-914. doi: 10.1038/s41386-023-01783-1. Epub 2024 Jan 4. PMID: 38177696; PMCID: PMC11039472.
Andrew Carry Kruegel, WO2021134086 (to Gilgamesh Pharmaceuticals Inc, Columbia University in the City of New York).

 

[funafternoon666]

interesting name...
(meanwhile in the k-hole: so what did you use? b l i x e p r o d i l)

and it is like only 1 isomer of 4fdck? how do you think this relates to 2fdck? that one I've tried on various occasions