^
It all depends on the league scoring. The leagues I play in qb's score a bunch more than rb's/wr's.
I haven't had time to analyze the scoring in this league thoroughly, but I know we're doing points per reception, so keep that in mind.
Go to My team, then edit auto pick strategy and even edit pre draft player rankings if you want to go in a little deeper. The autopick strategy will allow you to configure where you choose your positions and how many.
And I'd certainly get 2 qb's. Injuries, inconsistent play, and the bye week... You probably won't find a decent one left over.