• N&PD Moderators: Skorpio | someguyontheinternet

beta-methylene n-methyl phenethylamine

fastandbulbous said:
Why it's the same thing unless you eat a load of MAOI woith it, which isn't what's been asked (no ne of the PEA stuff you've mentioned in other threads without peer reviewed evidence of the evidence. I don't care hw many anecdotal things you say you have, it needs to be peer reviewed)

Fact of science any substrate taken in a high enough dose will overwhelm it's enzyme. For most adults this appears to be 1-1.5 grams.

Take it how ever you like.
 
From which source are you quoting the 1-1.5g figure from? I'm wondering as if it dose at that dosage, that means it's effectivly a competetive (ie reversable in that it is competing for occupancy of the active site of the enzyme & while in the active site that molecule of enzyme is unavailable for metabolizing any other compound) inhibitor of MAO-A with an IC50 dose of less than 1000mg. You'd think someone would have seen a comment about this property somewhere as it's clinically significant
 
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MAO-B, and likely it is such for a percentage of the populace but with variance some may need 2x or even 3x aid amount before results are realized

again as I explained above it is simply an entourage effect with the entourage being the same substrate and it indeed such entourage substartes which may not be classical inhibitors become de facto competitive inhibitors
 
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