Benzodiazepine Conversion Chart

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Benzodiazepine Conversion Chart


This chart was compiled from several online sources. Benzodiazepines (benzos) act differently upon different people, so please only use this chart as a loose guide. Always speak with a medical professional who is knowledgeable and experienced with benzo tapering before beginning a tapering plan. If you have been on benzo therapy for a long period of time and/or at a high dosage, do not attempt to stop usage without a taper. Seek medical advice in this situation. Benzos are cross-tolerant with Z-drugs, alcohol, barbiturates and other GABA-acting CNS depressants.



Diazepam 10 mg (anxiolytic/anticonvulsant/muscle relaxant; onset/time to peak: 1-1.5 hrs; 20-100 hrs [36-200 hrs]†) =




Alprazolam = .5 to 1mg (anxiolytic; onset/time to peak: 1-2 hrs; 6-12 hr half life)

Bromazepam = 6 mg (anxiolytic; onset/time to peak: 1-3 hrs; 10-20 hr half life)

Brotizolam = 0.25 mg (hypnotic; onset/time to peak: 0.5-2 hrs; 4-5 hr half life)

Chlordiazepoxide = 25 mg (anxiolytic; onset/time to peak: 1.5-4 hrs; 5-30 hr half life [36-200 hrs]†)

Clonazepam = 0.5 mg (anxiolytic/anticonvulsant; onset/time to peak: 1-4 hrs; 18-50 hr half life)

Clorazepate = 15 mg (anxiolytic/anticonvulsant; onset/time to peak: variable; 36-100 hr half life)

Delorazepam = 1 mg (anxiolytic; onset/time to peak: 1-2 hrs; 60-140 hr half life)

Estazolam = 2 mg (hypnotic; onset/time to peak: 1-5 hrs; 10-24 hr half life)

Etizolam = 1 mg (anxiolytic; onset/time to peak: 1-2 hrs; 6 hr half life)

Flubromazolam = .150mg (anxiolytic; onset/time to peak: 1-3 hrs; 12-20+ hr half life) -- note extremely potent, life-threatening adverse reactions seen with as little as 3mg

Flunitrazepam = 1 mg (hypnotic; onset/time to peak: 0.5-3 hrs; 18-26 hr half life [36-200]†)

Flurazepam = 25 mg (hypnotic; onset/time to peak: 1-1.5 hrs; 40-250 hr half life)

Flutoprazepam = 2 mg (hypnotic; onset/time to peak: 0.5-9 hrs; 60-90 hr half life)

Loprazolam = 1 mg (hypnotic; onset/time to peak: 0.5-4 hrs; 6-12 hr half life)

Lorazepam = 1 mg (anxiolytic/anticonvulsant; onset/time to peak: 2-4 hrs; 10-20 hr half life)

Lormetazepam = 1 mg (hypnotic; onset/time to peak: 0.5-2 hrs; 10-12 hr half life)

Medazepam = 10 mg (anxiolytic; onset/time to peak: 2-6 hrs; 36-200 hr half life)

Midazolam = 5-8 mg (hypnotic/anticonvulsant; onset/time to peak: 0.5-1 hrs; 3 hr half life)

Nimetazepam = 5 mg (hypnotic; onset/time to peak: 0.5-3 hrs; 14-30 hr half life)

Nitrazepam = 10 mg (hypnotic/anticonvulsant; onset/time to peak: 0.5-7 hrs; 15-38 hr half life)

Nordazepam = 10 mg (anxiolytic; onset/time to peak: 1.5-6 hrs; 50-120 hr half life)

Oxazepam = 25 mg (anxiolytic; onset/time to peak: 3-4 hrs; 4-15 hr half life)

Phenazepam = 1 mg (anxiolytic/anticonvulsant; onset/time to peak: 1.5-4 hrs; 60 hr half life)

Quazepam = 20 mg (hypnotic; onset/time to peak: 1-5 hrs; 39-120 hr half life)

Temazepam = 20 mg (hypnotic; onset/time to peak: 0.5-3 hrs; 8-22 hr half life)

Tetrazepam = 100 mg (muscle relaxant; onset/time to peak: 1-3 hrs; 3-26 hr half life)

Triazolam = 0.25 mg (hypnotic; onset/time to peak: 0.5-2 hrs; 2 hr half life)


Eszopiclone = 3 mg (6 hr half life)
Zaleplon = 20 mg (1 hr half life)
Zolpidem = 20 mg (2.6 hr half life)
Zopiclone = 15 mg (4-6 hr half life)


†[xx-xx] - denotes active metabolite(s) half life




http://www.emergency-medicine-tutor...ol-withdrawal/benzodiazepine-conversion-chart
http://www.dassa.sa.gov.au/webdata/resources/files/Benzo_Conversion_Chart.pdf
http://www.fpnotebook.com/psych/cd/BnzdzpnEqvlnts.htm
http://www.benzodocs.com/converter.php
http://www.dr-bob.org/tips/bzd.html
http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2125.2002.t01-10-01714.x/pdf
http://en.wikipedia.org/wiki/List_of_benzodiazepines