Opioids benadryl or tagamet better potentiator?

[sludgefactory101]

which one is the better potentiator in your opinion?

 

[Lichking83]

I've tried generic Tagamet, did not really notice much of a difference.

 

[enoughorangejuice?]

never tried tagamet.

but for antihistamines i find doxylamine to be better than diphenhydramine and cyclizine to be better than both.

 

[ErgicMergic]

Tagamet/WGFJ (act the same way, but WGFJ lasts longer) for reducing rate of elimination by inhibiting CYP2D6/CYP3A4 enzymes, benadryl for potentiating the nod and sedation, but anti-cholinergenics feel so nasty to me, and ruin the subtle nuances of the opiate high by "dirtying" it up.

 

[xxxyyy]

Tagamet/WGFJ (act the same way, but WGFJ lasts longer) for reducing rate of elimination by inhibiting CYP2D6/CYP3A4 enzymes, benadryl for potentiating the nod and sedation, but anti-cholinergenics feel so nasty to me, and ruin the subtle nuances of the opiate high by "dirtying" it up.

same with me. i've tried it with different antihistamines and different opioids but every time it dampened the euphoria. same with benzos. i know a lot of people who absolutely swear by the combination of heroin and flunitrazepam. i find both enjoyable on their own. together, eh. by this i mean the minority of non-retarded ones i've known who actually take the rohypnol orally.

also fun fact: it's common practice around here to mix a rohypnol into a shot of heroin. what is commonly believed and the lore on the street is that you have you first suck off the coating before you can shoot them. i mean virtually every junkie i ever talked to about this said this exact same thing. when i mention that flunitrazepam is nearly insoluble in water and no amount of saliva is gonna change that and all they're shooting is blue dye and filler they almost always get belligerent. GODDAMN YOU LITTLE PUNK I'VE BEEN BANGING ROOFIES WHEN YOU WERE STILL SWIMMING IN YOUR DADDIES BALLS!!!

 

[BiggDirty01]

Tagamet is an actual potentiator in terms of inhibiting liver enzymes that process the opiates out of your system. Diphen is more of a drug that is used to enhance the nod you will get from whatever your DOC is.