Bad spice causes kidney failure in Wyoming!

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THC2LSD

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Outbreak of kidney failure in Wyoming linked to ‘Spice’
Laura Zuckerman
Reuters US Online Report Domestic News

Mar 02, 2012 21:43 EST

(Reuters) - Three young people have been hospitalized with kidney failure and a dozen others sickened in Casper, Wyoming, in an outbreak linked to a batch of the designer drug Spice, authorities said on Friday.

State medical officials said the cause of the outbreak was under investigation but that Casper residents who sought medical treatment for vomiting and back pain had recently smoked or ingested a chemical-laced herbal product packaged as "blueberry spice." http://www.reuters.com/article/2012/03/03/usa-drug-illness-idUSL2E8E30QG20120303

I knew this was eventually going to happen. The government banned the early safer compounds, now more are turning to newer, potentially more dangerous compounds that often aren't even tested in mice.
This would never happen if cannabis were legal!
 
damn! This makes me glad I never used it. I have friends who do frequently use it though. I'm not sure why they don't just smoke bud?
 
PriestTheyCalledHim said:
damn! This makes me glad I never used it. I have friends who do frequently use it though. I'm not sure why they don't just smoke bud?
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I know the only reason I, and a lot of other people, fucked with synthetics was dealing with probation shit. Now that I'm off paper I'll never touch that shit again. I'm guessing some people smoke it simply because it is much cheaper than weed.
 
villian said:
I know the only reason I, and a lot of other people, fucked with synthetics was dealing with probation shit. Now that I'm off paper I'll never touch that shit again. I'm guessing some people smoke it simply because it is much cheaper than weed.
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Same, I fucked with it as a juvenile on probation and then got off and smoked weed all day,everyday before I got on adult probation. I hit from time to time now but much more responsibly than I did as a juvenile. As soon as I get off, I'm going back to regular.

IME, the majority of smokers prefer regular weed to synthetic. I think the biggest thing id weed is known to be one of the safest drugs out there, if not the safest whereas RC cannabinoids could have all sorts of side effects. I admit that I do feel stupid from time to time when I think about why I smoke synthetic but I just enjoy the general effects profile of cannabinoids more so than any other class of drugs. I don't ever use opiates or benzos, I have no interest but when it comes to cannabinoids, its quite hard for me to say no.
 
I think its possible it wasn't even a 'bad batch' just a reaction to the usual stuff that circulates. Thisstuff seems crazy bad for your health, like it just feels so so unhealthy on your digestion, throat, stomach, liver, kindeys, muscle spasms etc, headaches. They are all not so good things, no idea how people could smoke this shit for a year+
 
Ya that shits bound to have problems like this and probably many more to come. the thing is the fact that its legal is so atractive to people who don't realize how risky it can be. You can drive/walk around stoned a fuck smoking it everywhere and not have to worry at all about going to jail which is a huge weight of your shoulders compared to smoking weed. i smoked it on probation too for like a week and decided it didnt really even feel healthy and its not worth the risk.
 
Just smoke the real deal weed.............I know some people cant get the real stuff but screwing yourself over with all these unreliable chemicals isnt the way to go.
 
scary shit. the only time i smoked this garbage was when my gf's dads friend brought some over. he works in a hospital so thought hed give the spice a try and not telling me what it was we smoked some of it, and i felt like shit, really nasty feeling like almost pre trip anxiety, i wanted to say get that shit outta here! but i know he thinks its a good deal.
 
OTGee said:
I think its possible it wasn't even a 'bad batch' just a reaction to the usual stuff that circulates. Thisstuff seems crazy bad for your health, like it just feels so so unhealthy on your digestion, throat, stomach, liver, kindeys, muscle spasms etc, headaches. They are all not so good things, no idea how people could smoke this shit for a year+
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Possible, but it's unusual that so many cases happened in one small city from the same brand of 'blueberry spice'. I've smoked tons of spice and don't have any health problems that weren't already present. I actually enjoy the high synthetics provided, not as good as real mj but still pretty good if you get the dose right, and if mixed with real weed can give a high more like cannabis with the potency of the spice. I miss the old spice(no pun intended) with HU-210, JWH-018, and the other, they were closer to THC and didn't seem to cause as many health problems.

I wonder what brand it was? Was it called 'blueberry spice' or are they just trying not to say the brand? Was it homemade, a local blend, or a common brand?
 
Would be nice to know which synthetic compounds they actually ingested. Didn't see if they mentioned the brand name or not, but I'd stay away from all cannabinoids (except the real thing) for a while until more is known.

And I agree that no one would use these copycat designer drugs if not for prohibition. The only reasons I hear for using them are 1.) you can still pass a drug test and 2.) they're cheap and widely available. Two problems that could easily be resolved by decriminalizing the real thing.

IMO this incident sounds like a bad synth rather than a bad reaction to pure cannabinoids. Some nasty compounds can be left behind if these things aren't synthesized properly.
 
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apparently, even weed can fuck with the kidneys:

Dtsch Med Wochenschr. 2011 Aug;136(34-35):1720-2. Epub 2011 Aug 29.

[Cannabinoid hyperemesis syndrome inducing acute prerenal failure and electrolyte
disturbance].

[Article in German]

Bramstedt J, Dissmann R.

Medizinische Klinik II, Kardiologie und Nephrologie, Klinikum Bremerhaven
Reinkenheide, Bremerhaven. [email protected]

HISTORY AND CLINICAL FINDINGS: A 36-year-old patient presented to the psychiatric
clinic with presumed worsening of a chronic psychosis.
INVESTIGATIONS: Laboratory values revealed acute renal failure and electrolyte
imbalance. A further diagnostic work-up including urine analysis as well as
abdominal und retroperitoneal sonography was normal. DIAGNOSIS, THERAPY AND
CLINICAL COURSE: By exact history taking the clinical diagnosis of a cannabinoid
hyperemesis syndrome (CHS) was established. Symptomatic treatment with
intravenous fluids and electrolytes together with strict cannabis abstinence
completely resolved all symptoms and normalized all pathologic values.
CONCLUSION: Recreational use of cannabis is widespread. It may induce a widely
unknown syndrome characterized by nausea, vomiting and crampy abdominal pain
accompanied by frequent hot showers or bathing. This syndrome should be
recognized as a potential cause of acute prerenal failure.

© Georg Thieme Verlag KG Stuttgart · New York.

PMID: 21877303 [PubMed - indexed for MEDLINE]
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Cannabinoid hyperemesis syndrome is a real condition. Maybe it was the culprit here too?
 
THC2LSD said:
I wonder what brand it was? Was it called 'blueberry spice' or are they just trying not to say the brand? Was it homemade, a local blend, or a common brand?
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From my understanding, with this stuff, labeling means nothing. The same brand can be totally different at two different places. In fact, there are copycats of popular brands as the stuff is quite easy to produce and people trying to get attention will use VERY similar labeling as far as name goes to attract customers who may be on the fence about which to choose. The same went for "bath salts"-content varies from bag to bag really, in fact, the store could get the same packaging but the blend could contain different synths than the previous set of bags.
 
I agree the wiki is weak. Here's some primary sources:

NSFW:
1: Bagdure S, Smalligan RD, Sharifi H, Khandheria B. Waning effect of compulsive
bathing in cannabinoid hyperemesis. Am J Addict. 2012 Mar;21(2):184-5. doi:
10.1111/j.1521-0391.2011.00209.x. Epub 2012 Feb 7. PubMed PMID: 22332866.


3: Simonetto DA, Oxentenko AS, Herman ML, Szostek JH. Cannabinoid hyperemesis: a
case series of 98 patients. Mayo Clin Proc. 2012 Feb;87(2):114-9. PubMed PMID:
22305024.


4: Wild K, Wilson H. Cannabinoid hyperemesis. Emerg Med J. 2012 Jan;29(1):67-9.
PubMed PMID: 22186263.


5: Galli JA, Sawaya RA, Friedenberg FK. Cannabinoid hyperemesis syndrome. Curr
Drug Abuse Rev. 2011 Dec;4(4):241-9. PubMed PMID: 22150623.


7: Francis H. Emerging role of chronic cannabis usage and hyperemesis syndrome.
South Med J. 2011 Sep;104(9):665. PubMed PMID: 21886088.


8: Wallace EA, Andrews SE, Garmany CL, Jelley MJ. Cannabinoid hyperemesis
syndrome: literature review and proposed diagnosis and treatment algorithm. South
Med J. 2011 Sep;104(9):659-64. Review. PubMed PMID: 21886087.


9: Bramstedt J, Dissmann R. [Cannabinoid hyperemesis syndrome inducing acute
prerenal failure and electrolyte disturbance]. Dtsch Med Wochenschr. 2011
Aug;136(34-35):1720-2. Epub 2011 Aug 29. German. PubMed PMID: 21877303.


10: Bonnet U, Chang DI, Scherbaum N. [Cannabis hyperemesis syndrome]. Fortschr
Neurol Psychiatr. 2012 Feb;80(2):98-101. Epub 2011 Jun 20. German. PubMed PMID:
21692016.


11: Price SL, Fisher C, Kumar R, Hilgerson A. Cannabinoid hyperemesis syndrome as
the underlying cause of intractable nausea and vomiting. J Am Osteopath Assoc.
2011 Mar;111(3):166-9. PubMed PMID: 21464265.


12: Lieb M, Palm U, Nicolaus M, Reibke R, Baghai TC. [Cannabinoid-induced
hyperemesis]. Psychiatr Prax. 2011 Apr;38(3):147-9. Epub 2011 Apr 1. German.
PubMed PMID: 21462097.


13: Stuijvenberg MP, Ramaekers GM, Bijpost Y. [Cannabinoid hyperemesis syndrome].
Ned Tijdschr Geneeskd. 2011;155:A2880. Dutch. PubMed PMID: 21426598.


14: Schmid SM, Lapaire O, Huang DJ, Jürgens FE, Güth U. Cannabinoid hyperemesis
syndrome: an underreported entity causing nausea and vomiting of pregnancy. Arch
Gynecol Obstet. 2011 Nov;284(5):1095-7. Epub 2010 Dec 18. PubMed PMID: 21170540.


15: Miller JB, Walsh M, Patel PA, Rogan M, Arnold C, Maloney M, Donnino M.
Pediatric cannabinoid hyperemesis: two cases. Pediatr Emerg Care. 2010
Dec;26(12):919-20. PubMed PMID: 21131803.


16: Patterson DA, Smith E, Monahan M, Medvecz A, Hagerty B, Krijger L, Chauhan A,
Walsh M. Cannabinoid hyperemesis and compulsive bathing: a case series and
paradoxical pathophysiological explanation. J Am Board Fam Med. 2010
Nov-Dec;23(6):790-3. PubMed PMID: 21057076.


17: Aguilar-Urbano VM, Pérez-Aisa Á, Navarro-Jarabo JM, Sánchez-Cantos A.
[Cannabinoid hyperemesis]. Med Clin (Barc). 2011 May 21;136(14):650-1. Epub 2010
Oct 18. Spanish. PubMed PMID: 20961588.


18: Sullivan S. Cannabinoid hyperemesis. Can J Gastroenterol. 2010
May;24(5):284-5. Review. PubMed PMID: 20485701; PubMed Central PMCID: PMC2886568.


19: Sannarangappa V, Tan C. Cannabinoid hyperemesis. Intern Med J. 2009
Nov;39(11):777-8. PubMed PMID: 19912406.


20: Donnino MW, Cocchi MN, Miller J, Fisher J. Cannabinoid hyperemesis: a case
series. J Emerg Med. 2011 Apr;40(4):e63-6. Epub 2009 Sep 17. PubMed PMID:
19765941.


21: Ochoa-Mangado E, Jiménez Giménez M, Salvador Vadillo E, Madoz-Gúrpide A.
[Cyclical hyperemesis secondary to cannabis abuse]. Gastroenterol Hepatol. 2009
Jun-Jul;32(6):406-9. Epub 2009 May 27. Spanish. PubMed PMID: 19477551.


22: Budhraja V. Confirming the diagnosis of cannabinoid hyperemesis. Mayo Clin
Proc. 2009 May;84(5):483; author reply 483. PubMed PMID: 19411446; PubMed Central
PMCID: PMC2676133.


23: Watts M. Cannabinoid hyperemesis presenting to a New Zealand hospital. N Z
Med J. 2009 Feb 27;122(1290):116-8. PubMed PMID: 19319174.


24: Sontineni SP, Chaudhary S, Sontineni V, Lanspa SJ. Cannabinoid hyperemesis
syndrome: clinical diagnosis of an underrecognised manifestation of chronic
cannabis abuse. World J Gastroenterol. 2009 Mar 14;15(10):1264-6. PubMed PMID:
19291829; PubMed Central PMCID: PMC2658859.


25: Chang YH, Windish DM. Cannabinoid hyperemesis relieved by compulsive bathing.
Mayo Clin Proc. 2009;84(1):76-8. PubMed PMID: 19121257; PubMed Central PMCID:
PMC2664574.


26: Singh E, Coyle W. Cannabinoid hyperemesis. Am J Gastroenterol. 2008
Apr;103(4):1048-9. PubMed PMID: 18397435.


27: Wallace D, Martin AL, Park B. Cannabinoid hyperemesis: marijuana puts
patients in hot water. Australas Psychiatry. 2007 Apr;15(2):156-8. PubMed PMID:
17464661.


28: Alfonso Moreno V, Ojesa F, Moreno-Osset E. [Cannabinoid hyperemesis].
Gastroenterol Hepatol. 2006 Aug-Sep;29(7):434-5. Spanish. PubMed PMID: 16938265.


29: Roelofs J, Vorel SK, Vorel-Havelkova E, Brombacher PJ. [Cannabinoid
hyperemesis with the unusual symptom of compulsive bathing]. Ned Tijdschr
Geneeskd. 2005 Oct 15;149(42):2376. Dutch. PubMed PMID: 16261721.


32: Roche E, Foster PN. Cannabinoid hyperemesis: not just a problem in Adelaide
Hills. Gut. 2005 May;54(5):731. PubMed PMID: 15831930; PubMed Central PMCID:
PMC1774504.


33: Allen JH, de Moore GM, Heddle R, Twartz JC. Cannabinoid hyperemesis: cyclical
hyperemesis in association with chronic cannabis abuse. Gut. 2004
Nov;53(11):1566-70. PubMed PMID: 15479672; PubMed Central PMCID: PMC1774264.
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LogicSoDeveloped said:
From my understanding, with this stuff, labeling means nothing. The same brand can be totally different at two different places. In fact, there are copycats of popular brands as the stuff is quite easy to produce and people trying to get attention will use VERY similar labeling as far as name goes to attract customers who may be on the fence about which to choose. The same went for "bath salts"-content varies from bag to bag really, in fact, the store could get the same packaging but the blend could contain different synths than the previous set of bags.
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I Know that, but other may want to avoid that brand, kind of like warning about a bad bag of dope or bad xtc pill. It's better than nothing. Also many can't/won't order powders online to make their own, so a lot of people buy pre made one from liquorstores/smokeshops.In my experience with bath salts/spice certain brands are rather consistant in their content and effects, that is till a compound gets banned.
 
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