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Avoiding serotonin syndrome by going off SNRI temporarily?

lorlalalor

Greenlighter
Joined
Jul 18, 2023
Messages
3
Hi! My question is in the interest of harm reduction, please be nice :)

So I used to take mdma a lot in my early 20s, but I wasn't on any medication then.

I've been taking venlafaxine 75mg for a few years now though. Last year I was at a gig and tried to take a pinga with a relatively high dose (about 400mg) of md for the first time in half a decade after forgetting I was on an SNRI, and it did almost nothing, just made me sweat with almost no psychoactive effect. Luckily no serotonin syndrome, but truly was just a waste of money. I trust the person I got it from though, was definitely my brain and not the md.

Now, I have an event in 4 days that I really wanted to take some md at.

I haven't taken my effexor in 2 days either. So before I take my next dose, I was wondering, would going off my effexor in the lead up to the event (and just dealing with the brain zaps) allow me to take mdma and actually feel the effects instead of blunting them so severely? Obviously I don't want serotonin syndrome either but I also don't want to risk it for an impotent high anyway.

Thank you :)
 
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