Prozac is a drug that takes days, even weeks before it has suitable levels of serotonin to have any changes. So if your coming down from rolling and take a Prozac and think you feel relief, its just in your head. SSRI's are less of a problem with MDMA as compared to MAOI's when comes to Serotonin Syndrome. I believe in taking the right tool for the job. Xanax is the best way to end a night on MDMA or tripping for that matter. 5-htp doesn't cross the BBB so I'm still not sure why people take it. As for the Wellbutrin, this doesn't sound like a smart thing to do, but I don't think it will kill you, if that makes you feel better.