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Bupe Anyone else like me? (bupe)

I have read somewhere that a real low dose of bupe will actually increase the amount of the metabolite norbuprenorphine. Now let's think here for a moment, the metabolite I mentioned is a μ-opioid, δ-opioid, and nociceptin receptor full agonist, AND you are taking cyclizine which acts synergystically with norbuprenorphine. Back in the day, there was a drug called Diconal which was a mix of cyclizine and dipipanone and from what I have gathered, this was an amazing high. Now I am only speculating here, but perhaps you have somehow opened up a pandora's box into a substitution for diconal, but I am not a pharmacist, so take anything I say as hearsay. I was just trying to connect the dots. But it might explain the euphoria you're experiencing, given nor-b is full μ. I also just realized that perhaps norbuprenorphine has a higher affinity for the receptor, which would explain this even further. Hmm.
 
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Ramblin, I am as sure as hell and have spent enough years getting caned every way possible to know when I'm high, so no it's defo not in my head. And I'm not the only one apparently, I've had skagheads who wouldn't believe me give it a go and get just as fucked. I am not opiate naive (I'm on a treatment ffs!) and have done almost every opiate you could think of, many times, this for 5 years.
I think it does block when you're on 32mgs/day (which is absolutely fucking ridiculous, doctors could prescribe much less and the patients wouldn't feel any different) but take less than say 4 or 6mgs and it won't have a blockage effect or at least not that much.
I guess we're all different but this is just very strange. My keyworker was pretty surprised when I told him. I think there's a lot we don't know about bupe.
Balcony, yeah I've heard of Diconal and it seems it was excellent stuff - if similar to my bupe + cyclizine combo then yes indeed! I don't know much about chemistry though and can't really help here.
 
For me, it's a purely physical opiate feeling: I get the warm body sensation, (even after 8 years) but no "don't give a fuck" euphoria of other opiates. It's trained me to think straight, while getting just enough of the effect I need.
 
for my first fortnight on 2mg bupe i loved it and found the high great: a huge confidence,mood & energy boost. I kind of just got used to it after that and it started to just feel normal. Then 2 weeks later the magic returns again for no apparent reason.

Then i get used to it again and just feel normal as before. Yesterday i forgot to take it and by mid day i was wondering why i was feeling more depressed than i had done for years. Ah im missing the FUCKING BUPE.

Once that got into my bloodstream i felt better than normal. But now i think the magic has worn off, but the depression that hits me when i miss a dose makes me worry how im ever gonna be strong enough to get off this stuff.
 
BUPE!!!!!!1 saved my life but tread lightly ive been on 5 years ,i tried to come off 2 times its hell!! but yea bupe benzos my life i love the combo xanax klonopin and subutex cause i gotta buy em now dam they alotta money ! geeeeezeeee
 
A few days ago, I was hit by the reality of things, as I was 24hours off bupe and suffering badly, that I've spent fucking years doing the same thing everyday, and that I can't fucking stop. I mean, I knew it, but this time it really hit me hard and I realized I do have a problem, with bupe, and diazepam (I kept thinking I wasn't taking much but after running out of pills and counting, I worked out that I actually take about 60-70mg a day). Truth does hurt. I felt hopeless. I want to come off it NOW, I want that shit to get out of my system for good, and that being fed it by the chemist everyday only made me want & take more.
I'm thinking a lot and I wonder whether I could just show up at a mental institution and ask them to lock me up for a full month and not give me a single thing, not even paracetamol, pure cold turkey. I don't know if it's a good idea. But I know it's the only way I'll ever get clean. Do youse think that's possible? What do you think?
 
Hey there.
I decided to get off the bupe for good. In the past 48 hours I've only taken 0.2mg snorted (about 30 hours ago), and that was the last I'll ever take. When going to the chemist I just hold the pills between my teeth and spit them before they get under my tongue.
Was working all the while. Not feeling so good. Feeling raw, its mental, a lot of memories from a long time ago come back up and I start crying, then for some reason someone talks to me and I can't stop laughing, I mean, hysterical laughing, and I don't even find anything funny, pretty awkward.
My whole body feels sore already. Feeling weird as fuck. Can't stop blinking. Nightmares. It feels like my lungs, heart, neck, stomach, all hurt. Cold sweat. Also my nose is so running I gotta blow my nose every 2min.
It's been more than a year a half since I've stayed such a long time off the bupe.
 
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How much are you on dopemegently? Gotta learn to live without anything at all. I kept thinking for years, so what if I take something to get me through the day, as long as I'm happy this way? But I realised a few days ago that it just set me apart from everybody else around me. Once you realize you don't have feelings, that you're empty basically, you feel like shit.

I still haven't taken anything since my last post. I'm not feeling great, bad diarrhea and stomach cramps, bad sleep (I took 10mg diazepam and drank 2 guiness (I cant eat much) and managed to fall asleep, not for long though) and everything looks sharp. But I'm loving feeling. A song makes me cry or laugh, I'm hit by massive waves of emotion, I feel like I can relate to anyone. When I see someone smile, I feel like smiling too. I feel like a newborn baby, everything's so weird.
 
I can tell you that being stuck on buprenorphine may be much worse when it comes to getting off than being stuck on heroin/morphine etc. in some instances. And I mean both psychologically and physically. Bupe sticks to your opioid receptors much stronger than classic opioids do, but it doesn't activate them at the same rate. So in order to get the same magnitude of experience (or however you want to call it), you need to saturate your receptors with buprenorphine much more than it is with full agonists. On a longer basis it's worse for the receptors, I reckon. And you can easily find a forum devoted to people who got on buprenorphine and have terrible problems getting off it - and not because it's stronger or lighter than heroin/morphine etc., but simply because it IS a common problem to get below 2mg if you had been once placed on high-dose buprenorphine. I was initially placed on 8mg and at that time it seemed reasonable for me, because lower doses couldn't really hold me for 24 hours, so the first thing I thought about in the morning was how shitty I'm starting to feel. I really needed buprenorphine back then, because I couldn't stand the withdrawal from methadone and I started using needles again. But now I know that if I could make a choice again, I definitely wouldn't go higher than 2mg. Now I am theoretically on 2mg, but every 3-4 days I need to take 4mg, so the levels are kept at some rate. Otherwise the beginnings of withdrawal are attacking me too fast. It's a shame there are no low-dose Suboxone/Subutex pills and other buprenorphine pills mustn't be used as a substitute (i.e. I can't legally use 0.2mg or 0.4mg s.l. bupe pills indicated for pain to gradually lower my dose).

I perfectly understand why you might prefer buprenorphine to full agonists. Back in the days I similarly viewed codeine taken orally, to some point I preferred it to injecting it intramuscularly. I loved how subtle the high is and how gradually it kicks in, but for me it was too subtle and I found the real "relief" in morphine.
 
I feel when I am switching to using Suboxone after an extended use of my DOC, I could break down how it effects me into 3 stages. (note: I only dose 2 mg a time and usually dose 2 times a day except for the firs few days where its 3-4 times a day.)

1st stage - Last only 2-3 days and its basically because I am still in heroin acute w/d. When it peaks-around 1-1/2 after taking it sublingually, I feel alright, but that doesn't last long and I am otherwise just in a mild state of w/d. Like I can go to work and function, but it isn't much fun at all. And for he mos part I just mope around.

2nd stage - This is when I start getting a nice high from he Suboxone that last 2-3 hours and after that I will feel decent. The high is speedy and I get real talkative, I do enjoy it and is a nice change of pace from the highs I usually get. At the same time I star to notice things I didn't care so much about when getting high on the other stuff...music, socializing, libido all begin to come back. This sage last I would say 1-1/2 o 2 weeks.

3rd stage - At this point the high from Suboxone just keeps getting less and less noticeable. I start to feel just normal. This has been the tough thing for me, because if I could keep getting the high form it I would be all set. At this point I go one of 2 directions, either taper down over about 1 month and quit...or go back to the H. Guess which one happens more often?

I also want to mention that from 2nd stage on my pupils will constantly be pinned, and I mean more pinned than when I take H or oxy. Though I am not feeling anywhere near as high, and other side effects like constipation and itching are not there.
 
I agree RTrain i go thru the same 3 stages basically .. Only when im on the sub for about 45 days -2 mths..which i rarely make it to..but when i do its like the pink cloud finally evaporates from under me my natural opiate receptors have worn themselves out and basically shut down and boom fucking god awful depression sets in..ughhh
 
RTrain said:
3rd stage - At this point the high from Suboxone just keeps getting less and less noticeable. I start to feel just normal. This has been the tough thing for me, because if I could keep getting the high form it I would be all set. At this point I go one of 2 directions, either taper down over about 1 month and quit...or go back to the H. Guess which one happens more often?

I also want to mention that from 2nd stage on my pupils will constantly be pinned, and I mean more pinned than when I take H or oxy. Though I am not feeling anywhere near as high, and other side effects like constipation and itching are not there.
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Ian937 said:
I agree RTrain i go thru the same 3 stages basically .. Only when im on the sub for about 45 days -2 mths..which i rarely make it to..but when i do its like the pink cloud finally evaporates from under me my natural opiate receptors have worn themselves out and basically shut down and boom fucking god awful depression sets in..ughhh
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I used to refer to that as the 'two week itch' since that's how long after I switched to suboxone that I would feel like using again. The first week it's so easy to stay away from dope and you think it will be that way as long as you are on the sub, but after a while it gets boring and the subs don't provide the mood lift that they once did.
 
^exactly, I find that is the real difficult part. Getting by the first stage is tough, too. But it progressively gets better and you actually start to feel pretty good with the Subs so its not that bad and its only 2 or 3 days tops. The tougher part is what you called the 2 week itch and it just gets worse. The Subs start to go from giving you a 2-3 hour nice, energetic opiate buzz (which I find greatly enhanced with a cup of coffee), to a slight change that ends up being lackluster.

Ian937 said:
I agree RTrain i go thru the same 3 stages basically .. Only when im on the sub for about 45 days -2 mths..which i rarely make it to..but when i do its like the pink cloud finally evaporates from under me my natural opiate receptors have worn themselves out and basically shut down and boom fucking god awful depression sets in..ughhh
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I honestly never used them for longer than 45 days, maybe around 50 a most. So maybe there is a 4th stage if you go that long where its even less effective. I always either taper off or use again before that long. And Its like 6 to 2 in terms of how many times I have used again and I have tapered off. There also has been many times I used Subs for <1 week just to get money to keep using with no intention to actually stop in those times.
 
Rogg If said:
How much are you on dopemegently? Gotta learn to live without anything at all. I kept thinking for years, so what if I take something to get me through the day, as long as I'm happy this way? But I realised a few days ago that it just set me apart from everybody else around me. Once you realize you don't have feelings, that you're empty basically, you feel like shit.

I still haven't taken anything since my last post. I'm not feeling great, bad diarrhea and stomach cramps, bad sleep (I took 10mg diazepam and drank 2 guiness (I cant eat much) and managed to fall asleep, not for long though) and everything looks sharp. But I'm loving feeling. A song makes me cry or laugh, I'm hit by massive waves of emotion, I feel like I can relate to anyone. When I see someone smile, I feel like smiling too. I feel like a newborn baby, everything's so weird.
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Sorry, I forgot to mention I'm on 12 mg daily. Your right, I do feel apart, and I do feel like I'm emotionless. The thought of being completely straight is scary to me...addiction is the ultimate head fuck in that regard; I got to feeling I needed something to function as a human being from a young age and it's never left me. I congragulate you for getting it together; I envy the fact that your high on life right now, but you deserve it for having the balls to quit.
 
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I don't think anyone on bluelight HATES bupe. It's just not a recreational drug. There are a lot of heroin users on here who Suboxone was a life saver for. I'm on it right now. although I'm still struggling with addiction. I just spent my first weekend in years clean and not caring about junk - because I had Subxone (and some good L haha). I've been resistant in the past to go on i, because I'm so attached my opiate buzz. It's my best friend. But this is not a sustainable life style anymore. So I'm so thankful for Suboxone. Even my parents give me money for it. they would rather see that than junk. I almost lol'd but not a laughing matter. I think where all the hate comes from is people out there who want to abuse it, or maybe a little jealousy because they can still use it recreationally. But it's saved so many peoples lives, that it deserves a little more respect than that.
 
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