There isn't much discussion to be had, amphetamines take from the future and give you what you want now. Even at low doses the mechanism of the drug means that over time you deplete your body's reserves of dopamine and noradrenaline if you don't give it rest, causing damage to the receptors over long periods of time and it just loses its pop..
Something as good as the amphetamine rush can surely not last forever it common sense.
Although it is not as ravaging as the media portrays but depression and anxiety can be small problems that cause your life to head in the wrong direction, You dont have to be bat shit insane to notice the eroding effect of amphetamine. you can never justify every day use in my opinion as it can not be sustained without impacts on personality and emotions, even low dose treatment for ADHD has changed some of my friends forever.
You cant eat Pizza and Burgers all day without getting coronary artery disease at 50, so imagine whats drugs do