Misc Antihistamines Mega Thread

[barillas]

Orphenadrine in high dose is very bizarre due to dual mechanism of action as anticholinergic/nmda antagonist.

What's the explanation for the mild euphoria on antihistamines like diphenhydramine?

 

[BrugmansiaFreak]

Orphenadrine in high dose is very bizarre due to dual mechanism of action as anticholinergic/nmda antagonist.

How much?
Each pill I have contain metamizole (300mg) + caffeine (50mg) + orphenadrine (35mg)
How much you took and how much is safe for me?

 

[simstim]

How much?
Each pill I have contain metamizole (300mg) + caffeine (50mg) + orphenadrine (35mg)
How much you took and how much is safe for me?

I don't know about the other drugs in yours. Mine was time release and 100mg orphenadrine only. I chewed 7 or 8 to get high

 

[negrogesic]

On a side note, interesting that the wikipedia article on orphenadrine (and associated citation) describe PCP as having micromolar affinity for NMDA when its definitely in the nanomolar range

At least i found it interesting

 

[Jabberwocky]

Alcohol withdrawal (treatment)
Parenteral hydroxyzine is indicated in the acute or chronic alcoholic with anxiety withdrawal symptoms.

Get out!?!?

Okay here is what is going on here in my dungeon: I have been without alcohol for 2 days and 2 nights. Due to lack of money. A little bit of money will come tomorrow, but i would really fucking LOVE to sleep well before that. Does this count:

Telfast (fexofenadine)

 

[BrugmansiaFreak]

I don't know about the other drugs in yours. Mine was time release and 100mg orphenadrine only. I chewed 7 or 8 to get high

God! Pure orphenadrine, right? I'd love to read a trip report!