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Antidepressants and Psychedelics???

theevilkitty

Greenlighter
Joined
Mar 16, 2011
Messages
6
Ok, so I was prescribed Zoloft about 6 weeks ago. i dont really like it. I mean it helps with my depression, but its effects on my drug use arent exactly to be desired. I didn't have much choice as to what antidepressant I was being put on because I'm 16, and it was my parents' idea. But next time I go to the doctor I plan on trying to get it switched to something else by saying its not working for me. Something that doesnt effect my "recreational activities" as much.

I've noticed that when I'm on amphetamines it drastically increases the effects. And I'm completely ok with that, in fact I love it. Just taking a little bit of Vyvanse (unprescribed) makes me feel like I'm on crack.

When I smoke weed it pretty much turns me into a lifeless blob. Perfect candidate to be a rape victim. Not what I want at all

But my main concern is its effects on psychedelics. I'm just very recently getting into tripping. I did acid for the first time a week ago. 5 hits. I had an awesome trip. But yesterday I ate 450 morning glory seeds (LSA) and nothing happened. The seeds were fresh and I just chewed them to mush and ate them. It was gross. The tasted really bitter and acidic. I was expecting to get really nauseas and then trip. But nothing at all happened. After 3 hours I had no sickness and definitely no trip or high feeling whatsoever. So I gave up. I then did some research and found out that my medication was probably the cause. Apparently it decreases the effects of LSD, LSA, psilocybin, and MDMA. All of which are my personal favorites.

So my question is. Are there any antidepressants out there that won't effect these drugs? or even better, increase the effects of these drugs?
 
Not all tricyclics potentiate psychedelics. Doxepin seems to significantly decrease the intensity of a LSD trip. I dropped a 180ug blotter (Avatars) and barely felt any effects after 1-2 hours. Everyone else who got blotters from the same source was tripping balls from 1. And I handled it carefully, to not lose potency.

Doxepin doesn't decrease the effects of MDMA though. It's supposed to be neuroprotective against MDMA induced neurotoxicity.
 
I think that they can vary.

When I first took LSD I was on prozac and nothing was blunted at all and I still tripped very hard on the acid.

A friend of mine was on Effexor and he was one of the biggest potheads I know but we took some shrooms together 1.5g each and smoked some herb, and he didn't trip that much at all unlike how I was getting a +++. I was not on any sort of SSRI or anti-depressant or medication at all when I ate mushrooms.
 
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It depends on the person I think. I'm on a generic form of lexapro but only at 20 mgs I think and I trip just fine. I even had some molly last weekend and rolled really good. I tripped before the antidepressants so I know how well I can. Also there was this one time I didn't roll on ecstasy but I believe it was because I had a bunk pill.

Well next week I'm going to the doctors I think I'm going to get off this antidepressant. I'm still depressed but I rather not take a pill that messes with the way my body works. To be honest it doesn't even help me.

Also I'm seventeen and you're allowed to pick which pill you go on. Trust me I was allowed to but my mom didn't want me to go on prozac because how it effected my sister so she was worried so I listened to her. Yet you don't have to go on anything because your parents told you to.
 
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