I am searching for some information for the use of antidepressants and neuroleptic agents in the treatment of insomnia.
Can there be a trend observed? Can they ever displace the benzos?
During my search, I found that not only the antihistaminic properties are responsible for the hypnotic effect of such drugs. There is often the 5-HT2A antagonism speculated also to be involved in the sedation.
Has anybody a good reference for sedating effects of 5-HT antagonists?
Thanks,
EN21
Can there be a trend observed? Can they ever displace the benzos?
During my search, I found that not only the antihistaminic properties are responsible for the hypnotic effect of such drugs. There is often the 5-HT2A antagonism speculated also to be involved in the sedation.
Has anybody a good reference for sedating effects of 5-HT antagonists?
Thanks,
EN21