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Stimulants Amphetamines, how much is too much?

Ksa said:
Ya that's too much. I would cap Adderall to 60mg daily for non toxic effects. What did you do all this time while you were on Adderall from 9PM to now?
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Not a whole hell of a lot. A little studying, I took some pictures of my car and edited them after cleaning it, and that's about it.
 
My HR is all over the place right now. It will stop completely for a couple seconds, then jump up to a rate of 140+ and everywhere in between.

I also have pretty orthostatic hypotension whanever I get up, which I assume is likely from an adrenal insuffeciency.
 
RR279 said:
Not a whole hell of a lot. A little studying, I took some pictures of my car and edited them after cleaning it, and that's about it.
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You've got to be shitting me...man, you're doing it all wrong lol you gotta stop wasting the doses.
 
Ksa said:
The reason why you have a headache is because you planned the whole thing wrong. If at all...you should start at 8:00am, stop taking anything at 3:00pm, dose opioid at 6:00pm and at 10:00pm and go to bed at 1 or 2 am so the comedown occurs during sleep. Also, make sure nothing wakes you up the next morning, that includes alarms, clocks we. make sure you wake up naturally and sleep a lot that night. You can't start shit up at 9 pm lol you're adding jet lag to the whole thing.

Sleeping will remove the headache. If you can't sleep make a punch of like, multivitamins, minerals, water, famotidine hydrochloride 10mg, Tylenol 500mg, codeine 60mg, omega 3, drink and try to sleep.
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I have a screwed up sleep schedule, partly due to my amp use and partly due to the fact I'm a night owl. 7AM-3PM is my 'normal' schedule.
 
until you start staying up two-three days at a time, i wouldn't sweat it.
if you feel uncomftorable with the amount you're doing you might want to cut back, but i don't think you have much to worry about.

this is coming from someone who shoots large amounts of crystal meth at least twice a day though so you might want to get a second opinion but honestly i think you're good.
 
phatass said:
i just know that amphetamines are very dangerous for the brain, i ave no scientific evidence to back it up but i'm sure if you googled i, you'd find loads of stories of peope going of the rails from adderrall and siilar amps, you're paying with fire
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Amphetamines are clearly neurotoxic if you use them recreationally. That is, if you are chasing the dopamine high. The only reason they are still commonly prescribed for those with ADD is since their levels of PFC Dopamine are low, and low doses of amps bring those low levels back up to normal without killing off Dopamine receptors.

Take an abusive dose that gets you "tweaked" and euphoric, ADD or not, and your DA receptors curl back and die off through DA excitotoxicity. The ADD individual will need a slightly higher recreational dosage since their PFC DA level is lower than those who are "normal transmitters," but they can get tweaked and neurotoxic just the same at a proportionally higher dosage.

Amp psychosis is the last stage of amp abuse: even if you never go psychotic, and sleep and eat normally, you can still damage your dopamine receptors, the ones responsible for trasmitting the neurotransmitters that are the very essence of life, or kefi, as the Greeks call it.

Without proper DA activity, what do we really have in this world? Take care of your brains and use amphetamines medicinally only, and if you must abuse them (very bad idea), then keep your dosages as low as possible to reduce (not eliminate) harm to your brain's PFC.
 
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ADD suffers get the same effects from amphetamines as everyone does. It's just amphetamines reduce symptoms and makes it easier to function. It will improve concentration in regular people too. I don't think there's any proof that dopamine levels are lower in ADD, it just so happens that drugs that raise dopamine are effective for ADD.

OP, 200mg a day is tweaker doses. I don't think you'll have a problem with neurotoxicity, but amphetamines can make you crazy and addicted if abused. Either take 60mg or less a day, or quit. Or become a tweaker. Up to you.
 
Am I the only one who doesn't think the word tweaker has a negative connotation? I've always just used it to describe anyone who likes to tweak or use methamp, but it seems like on these boards some people use it as a negative thing... just something random I've noticed. In my own life though, it's always just been how people refer to fellow users of methamp.

I agree that dosing 200mg a day is asking for trouble both short and long-term, even with regular old amphetamine. Good posting EM.
 
Perhaps it'd be worth the OP's time to investigate supplements (both natural and pharma) that either potentiate a smaller amphetamine dose or mitigate some of the side effects of high doses (excitotoxicity, peripheral overstimulation, etc)? I personally have benefitted greatly from substances like DXM, magnesium (glycinate, or any kinds except oxide and citrate), Selegiline, Memantine, b12 as methylcobalabin (sp?), all other b vitamins, guanfacine, pqq, and a whole host of other orthodox daily vitamins and supplements.
 
OP, it's time to take a sabbatical, and a long one at that. Take a break, listen to the waves, read, etc. The important thing is to stabilize your health and your tolerance to the drug. Once you get to the point of needing ungodly amounts of a drug (I.E 80MG's and up - Amphetamine) to feel needed effects, its time to reevaluate. I'm not saying you can never take the drug again but its up to you whether you have the will power to use the drug responsibly.

This doesn't come down to guilt that subconsciously lives inside of us as one other poster mentioned. This comes down to HR. Its that simple. You're taking a serious toll on your body. Take a step back and reexamine things. When the time comes (4-6 months), you decide if you can handle the drug responsibly or not. But, for now, ask yourself why you're taking such a high amount in the first place. What is it you're chasing? In the end, were all chasing something. Self indulgence resides in all of us. Take care and keep us posted.

Cheers

Tomer
 
tricomb said:
Am I the only one who doesn't think the word tweaker has a negative connotation? I've always just used it to describe anyone who likes to tweak or use methamp, but it seems like on these boards some people use it as a negative thing... just something random I've noticed. In my own life though, it's always just been how people refer to fellow users of methamp.
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By tweaker I mean one who abuses or is addicted to amphetamines.If he said he smoked cocaine a lot he'd be a crackhead. Just the name. Some can handle the lifestyle, others get ruined by the addiction. Shit I don't care what people do, I like meth and adderall too=D!I could remember popping dexies like candy.

OP, are you happy doing that much adderall? Is it too expensive, is it interfering with you life or health. If your not happy, and your drug uses is having a negative effect, you might want to consider quitting. The memory/cognitive problems are from being spun, should go away when you quit and rebound from the depression afterwards.Then if you still have ADD take 60mg or less a day.Maybe switch to (dex)methylphenidate? Although if you can't quit, I could understand why.If you want to get high, cool, it's your choice. When doing uppers it's important to force yourself to eat, take vitamins, get sleep(preferably every day, or at least every two days), and maintain hygiene.
 
Well if the monkey studies are to be believe its roughy 40mg/day where things start down regulating, though apoptosis is kind of hard to conclusively prove in higher animals. My advice: check out my thread on the topic, start a steep taper, and maybe switch to MPH or modafinil if you need something else in the meantime.
 
Well, I wasn't able to get to sleep until 9AM this morning (36 hours after the binge started.) However, I was only 'high' for about 18-20 hours. I slept 10 hours, got a couple thousand calories in, and just started another binge about an hour ago (2:30 AM.) I plan to stop at 80mg but we'll see. FWIW I've only ever had binges exceeding 140mg about 10x since I started last year and weigh 200 lbs with a good amount of muscle mass, so although it definitely is a problem it's not QUITE as bad as some might of implied.

THC2LSD said:
OP, what do you mean by 10-15 hour binge? Is it like 60mg xr 4 times a week with sleep, or like 200mg for days on end?
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Seperate binges.

Ksa said:
Maybe it's just anxiety. Since human beings define their reality through pain and misery, it is not uncommon for someone to feel guilty when enjoying something. Examples abound: sex, drinking, watching sports, porn, masturbation etc. Religion doesn't help either.

Here's the good news. Guilt is not real, it's a chemical reaction that occurs in your brain, designed to blind you from the truth. The truth is that, as long as your habit is healthy, it's not wrong. In fact, it may be healthier than everything else, you don't know. And if it's not healthy, make it healthy. You got a brain, use it. Read chemistry, read read read read. Understand. When you don't understand you start being afraid and feeling guilty for having fun.
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I have no regrets about doing drugs in general, it's the fact that this one in particular is getting unhealthy and that's what I'm concerned about.

ErgicMergic said:
Amphetamines are clearly neurotoxic if you use them recreationally. That is, if you are chasing the dopamine high. The only reason they are still commonly prescribed for those with ADD is since their levels of PFC Dopamine are low, and low doses of amps bring those low levels back up to normal without killing off Dopamine receptors.

Take an abusive dose that gets you "tweaked" and euphoric, ADD or not, and your DA receptors curl back and die off through DA excitotoxicity. The ADD individual will need a slightly higher recreational dosage since their PFC DA level is lower than those who are "normal transmitters," but they can get tweaked and neurotoxic just the same at a proportionally higher dosage.

Amp psychosis is the last stage of amp abuse: even if you never go psychotic, and sleep and eat normally, you can still damage your dopamine receptors, the ones responsible for trasmitting the neurotransmitters that are the very essence of life, or kefi, as the Greeks call it.

Without proper DA activity, what do we really have in this world? Take care of your brains and use amphetamines medicinally only, and if you must abuse them (very bad idea), then keep your dosages as low as possible to reduce (not eliminate) harm to your brain's PFC.
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THAT is what I'm concerned about. The fact that I have severe ADHD and am naturally prone to depression leads me to believe that I got the short end of the stick in regards to dopamine when I was born and I'm making it even worse with my little habit.
 
Also, does anyone have any iinks to info on Amp neutoxicity and the like?
 
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