a friend of mine swears by taking some propranolol before taking any upper. he swears it greatly potentiates the effects of the uppers. i have not tried it yet (although i have some bisoprolol at my disposal) and always thought it's bullshit, aside from the beta blockers helping with the negative cardiovascular effects. but i don't know enought about the pharmacodynamics to be sure. so could someone with more insight into this enlighten me?