Alcohol Alcohol Megathread

[X11400]

Excellent description of what's the problem with it.

What “problem”?

 

[polymath]

What “problem”?

Even the chemicals that are actually used in medicine as inhalation anesthetics, can cause deadly cardiac arrhythmias or make your airways go to a spasm and stop your breathing. In the operating room there's at least the equipment to handle that kind of a situation. And the average inhalant abuser can be stupid enough to even try to smoke tobacco when intoxicated on toluene and make the solvent vapors explode.

 

[quaalMan]

And the average inhalant abuser can be stupid enough to even try to smoke tobacco when intoxicated on toluene and make the solvent vapors explode.

I've never found a great source for it (Here is one place, but I don't see references), but during the temperance movement when alcohol was overtaxed people substituted with diethyl ether. The fact that ether boils near room temperature, coupled with the fact people used fire stoves/heat...you can guess the results.

 

[X11400]

Even the chemicals that are actually used in medicine as inhalation anesthetics, can cause deadly cardiac arrhythmias or make your airways go to a spasm and stop your breathing. In the operating room there's at least the equipment to handle that kind of a situation. And the average inhalant abuser can be stupid enough to even try to smoke tobacco when intoxicated on toluene and make the solvent vapors explode.

Well I doubt acetone would cause these arrhythmias significantly more so than ethanol, however you might be right on that toluene hypothesis and I might look further into the safety of “methyl benzene” if you don’t have a source for the safety (even though I don’t plan on ingesting “methylbenzene”.

 

[X11400]

Did any of you guys click the gif? That was me at one point. I didn’t chug the whole bottle, but I ingested isopropanol and later after ingestion, my breath was sweet like acetone. So I now want to ingest this hydrocarbon on its own without being a metabolite of an alcohol.

 

[polymath]

Well I doubt acetone would cause these arrhythmias significantly more so than ethanol, however you might be right on that toluene hypothesis and I might look further into the safety of “methyl benzene” if you don’t have a source for the safety (even though I don’t plan on ingesting “methylbenzene”.

The worst inhalants in terms of the arrhythmia risk are propane, butane and some freons. In the past, cyclopropane gas was used as a general anesthetic and it did also sensitize the heart for adrenaline and increase the heart rate. It's not used anymore because it's flammable and can explode from an electric spark.

Did any of you guys click the gif? That was me at one point. I didn’t chug the whole bottle, but I ingested isopropanol and later after ingestion, my breath was sweet like acetone. So I now want to ingest this hydrocarbon on its own without being a metabolite of an alcohol

I don't think that is a good idea at all. We can't know how badly acetone irritates the stomach when ingested, in the worst case it could cause a bleeding ulcer.

 

[X11400]

The worst inhalants in terms of the arrhythmia risk are propane, butane and some freons. In the past, cyclopropane gas was used as a general anesthetic and it did also sensitize the heart for adrenaline and increase the heart rate. It's not used anymore because it's flammable and can explode from an electric spark.



I don't think that is a good idea at all. We can't know how badly acetone irritates the stomach when ingested, in the worst case it could cause a bleeding ulcer.

I doubt that this ulcer would occur significantly more so (acutely) than chronic alcohol usage or drinking 95% ethanol. But I don’t know, maybe you’re right. The “floor” is yours for citing your extraordinary claims. Now, if you are true about acetone basically instantly causing bleeding ulcers, then I’d propose dilution to counter this effect.

 

[sekio]

There's a recipe on Erowid detailing the use of acetone as a solvent for Salvia divinorum extractions as well as tinctures. The report seems to demonstrate that said tinctures are not as effective as one would like, and provides evidence that between 0.1 mL and 1mL acetone can be held in the mouth without too much discomfort.

People are reluctant to consume acetone, although with an oral LD50 of 5800 mg/kg in rats (Oxford University 2008a), this chemical has relatively low toxicity. Acetone is a natural metabolic by-product in the human body and is present in blood and virtually every organ and tissue, as well as in other plants, animals, and insects (CCOHS 2008a).The Canadian Centre for Occupational Health & Safety reports no or only minor effects in people ingesting up to 20 grams per day (!) for several days (CCOHS 2008b).

Net acetone would not be expected to cause ulcers. I thought those were H.pylori infections. Acetone, like ethanol, it'd expect would just give regular old heartburn.

 

[X11400]

There's a recipe on Erowid detailing the use of acetone as a solvent for Salvia divinorum extractions as well as tinctures. The report seems to demonstrate that said tinctures are not as effective as one would like, and provides evidence that between 0.1 mL and 1mL acetone can be held in the mouth without too much discomfort.

People are reluctant to consume acetone, although with an oral LD50 of 5800 mg/kg in rats (Oxford University 2008a), this chemical has relatively low toxicity. Acetone is a natural metabolic by-product in the human body and is present in blood and virtually every organ and tissue, as well as in other plants, animals, and insects (CCOHS 2008a).The Canadian Centre for Occupational Health & Safety reports no or only minor effects in people ingesting up to 20 grams per day (!) for several days (CCOHS 2008b).

Net acetone would not be expected to cause ulcers. I thought those were H.pylori infections. Acetone, like ethanol, it'd expect would just give regular old heartburn.

Well, both ethanol and acetone are dehydrating compounds in the human body so one would expect chronic usage to cause stomach ulcers. Anecdotally I know of an alcoholic who bleeds in his stomach lining “all the time”.

 

[X11400]

Well, both ethanol and acetone are dehydrating compounds in the human body so one would expect chronic usage to cause stomach ulcers. Anecdotally I know of an alcoholic who bleeds in his stomach lining “all the time”.

I’m just skeptical on one’s claim that acute acetone ingestion would cause significant ulcers.

 

[sekio]

In my learning, I understood that ulcers are most often caused by bacterial infections, and occasioanlly also NSAID drugs which inhibit COX1 and hence reduce protective mucus production.

I don't think you get ulcers, per se, from drinking diluted alcohol occasionaly. Maybe you'd get an upset stomach overall, but I would not expect major damage unless you were a habitual, daily acetone drinker, and took it neat.

 

[X11400]

In my learning, I understood that ulcers are most often caused by bacterial infections, and occasioanlly also NSAID drugs which inhibit COX1 and hence reduce protective mucus production.

I don't think you get ulcers, per se, from drinking diluted alcohol occasionaly. Maybe you'd get an upset stomach overall, but I would not expect major damage unless you were a habitual, daily acetone drinker, and took it neat.

Agreed. There is a high probability that we are correct on the difference between acute and chronic damages of these substances, however this concern is open to further investigation.

 

[d1nach]

Im almost positive he used editing and drank water.

 

[X11400]

Im almost positive he used editing and drank water.

Well I didn’t, and I was drunk and slightly dissociated (more so than ethanol).

 

[Jabberwocky]

Hey guys so I was wondering how “safe” it is to occasionally get wasted while on prescribed Prozac for anxiety (not specifically depression)? I’m on 20mg daily and if I do drink it’ll only be like 1-2 days every other weekend or so. I’ve only drank tequila and usually max out at 7 (1oz) shots if in quick succession. I’ve read about how alcohol basically reduces the effectiveness of Prozac while causing increased sedative effects, but the only information I can find about drinking on Prozac concerns alcholics or daily drinkers which are not representative of me.

 

[MsDiz]

It’s not just alcoholics that experience those side effects from mixing them. It’s not advisable to drink whilst on Prozac. It will increase sedation, it will interfere in how your medication works and it will increase side effects from the Prozac.

 

[Akoto]

I'm a medium heavy drinker. Never two nights in a row, try to space it out as much as I need to. I drink probably 15 beers (or equivalent in whiskey) two or three times a week.

Last night I bought just whiskey (tired of too much carbs/having to go piss every 20 minutes) and just started doing shots.
Crazy thing is I was completely sober until I was almost 1/2 done the bottle. Like no effect at all. I managed to get drunk but I almost finished the bottle, which is unheard of for me.

Question is why did pure whiskey not work? Also why does "mixing" different types of alcohol give a stronger effect?

Like I said it's mostly beer but I've been switching over to whiskey for a number of reasons.

 

[jhjhsdi]

Were you sat in the same spot doing shots?
Sometimes I can sit and do loads of shots and don't feel them until I get up to go piss or something. Can be dangerous the way it all kicks in at once lol.

Next time do a shot, get up, do a lap of your room/apartment/house whatever. Or walk outside for a cigarette or fresh air. Then come back, do another 1 or 2, then repeat the walking around.

That'd be my guess.
It's weird how beer hits you quicker than spirits sometimes. I heard it's something to do with the bubbles but I don't know if that's just speculation

 

[Akoto]

^^ That had occured to me. Started smoking after ever other shot and it helped a little.

 

[jhjhsdi]

Also try mixing it with a little bit of something fizzy/sugary like Coca-Cola, lemonade etc...

I think the sugar helps it get into your blood stream quicker. It does with ingesting magic mushrooms anyway (ie: a sugary mushroom milkshake hits harder/quicker than a mushroom pizza)