Al-37350a

[DylanG204]

This drug selectivley activates 5-HT2A receptors well and is an interesting looking compound , my guess is that this is phycoactive but cannot find any reports or info on it.

http://en.wikipedia.org/wiki/AL-37350A

AL-37350A (4,5-DHP-AMT) is a tryptamine derivative which acts as a potent and selective agonist for the serotonin receptor 5-HT2A, with a Ki of 2.0 nM, and moderate selectivity over the related 5-HT2B and 5-HT2C receptors. It has been shown to have ocular hypotensive activity in animal models, suggesting it may be useful for the treament of glaucoma.[1]



If i ordered a custom synthesis do you think it would be a worth while high?

 

[Solipsis]

Not a clue but the tricyclic structure may indicate a little higher cost to synthesize. I personally would discourage this kind of 'ad hoc' exploration of anything that activates 5-HT2A receptors. Have you researched it's effects on receptors other than serotonergic ones? Because they are not mentioned in this summary.

I know that any new drug has to be tried by pioneers at some stage and for successful and worthwhile drugs that have been discovered we sort of owe it to those who started trying them... but it's better if those people are underground chemists who understand a whole lot about these things and don't come here to ask about custom synths.

Be wary. Much more wary.

 

[Roger&Me]

It looks hideous :D

It's basically 5-MeO-a-MT with a bunch more steric bulk in a position not known for accomodating it well (see the 4,5-MDO-T's).

 

[Thorns Have Roses]

No what should I take/buy threads, this includes speculative pharmacology. Not to damper your enthusiasm man, but put the breaks on the thread creation and consider potential topics more carefully, and how they fit into the system we have here.